SCHEMBL6672705

SCHEMBL6672705

O=COC1(F)CC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL990275 0.88
SCHEMBL2031587 0.88
SCHEMBL3580850 0.86
SCHEMBL9947849 0.69
SCHEMBL670417 0.63
SCHEMBL9019386 0.63
SCHEMBL31193790 0.63
SCHEMBL61083 0.62
SCHEMBL1140316 0.62
SCHEMBL714458 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118480003-A Preparation method of fluoroalkylated quinoline diketone compound 哈尔滨工业大学(深圳)(哈尔滨工业大学深圳科技创新研究院) 2024-08-13 CN claimed
CN-116640043-A Synthesis method of 1-fluorocyclopropane carboxylic acid 岳阳市康利医药化工有限公司 2023-08-25 CN claimed
CN-116535305-A Preparation method and application of 1-fluorocyclobenzoic acid 佛山奕安赛医药科技有限公司 2023-08-04 CN claimed
CN-110818552-B Preparation method of 1-fluorocyclopropane carboxylic acid 南京合巨药业有限公司 2022-04-22 CN claimed
CN-110818552-A Preparation method of 1-fluorocyclopropane carboxylic acid 南京合巨药业有限公司 2020-02-21 CN claimed
EP-0436348-B1 Pyridyl cyclopropane derivatives with fungicidal activity ZENECA LTD (GB) 1996-11-13 EP claimed
EP-0436348-A2 Pyridyl cyclopropane derivatives with fungicidal activity ZENECA LIMITED (GB) 1991-07-10 EP claimed
US-12630521-B2 Arylamides and methods of use thereof GENZYME CORPORATION (US) 2026-05-19 US disclosed
EP-4692079-A1 CYP11A1 INHIBITOR AND USE THEREOF Xizang Haisco Pharmaceutical Co., Ltd. (CN) 2026-02-11 EP disclosed
CN-120136870-A GLP-1 receptor targeting compounds and uses thereof 信达生物科技有限公司 2025-06-13 CN disclosed
WO-2025119206-A1 GLP-1 RECEPTOR TARGETING COMPOUNDS AND USES THEREOF FORTVITA BIOLOGICS INC. (KY) 2025-06-12 WO disclosed
CN-119866338-A Tyrosine kinase 2 inhibitors and uses thereof 渤健马萨诸塞州股份有限公司 2025-04-22 CN disclosed
CN-119707984-A Pyrazolotriazine and pyrazolopyrimidine derivative, preparation method thereof, pharmaceutical composition and application thereof 中国科学院上海药物研究所 2025-03-28 CN disclosed
CN-110818552-A Preparation method of 1-fluorocyclopropane carboxylic acid 南京合巨药业有限公司 2020-02-21 CN disclosed
CN-110818552-A Preparation method of 1-fluorocyclopropane carboxylic acid 南京合巨药业有限公司 2020-02-21 CN disclosed
CN-110818552-A Preparation method of 1-fluorocyclopropane carboxylic acid 南京合巨药业有限公司 2020-02-21 CN disclosed
JP-2004210738-A DERIVATIVE OF FLUOROCYCLOPROPANE CARBOXYLIC ACID DAI ICHI SEIYAKU CO LTD 2004-07-29 JP disclosed
EP-0436348-B1 Pyridyl cyclopropane derivatives with fungicidal activity ZENECA LTD (GB) 1996-11-13 EP disclosed
US-5126338-A FUNGICIDES WHICH ARE N-PYRIDYL-CYCLOPROPANE CARBOXAMIDES OR DERIVATIVES THEREOF IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1992-06-30 US disclosed
EP-0436348-A2 Pyridyl cyclopropane derivatives with fungicidal activity ZENECA LIMITED (GB) 1991-07-10 EP disclosed