Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13210652 | 0.83 | ALDH1A1 (0.60) | KDM5BCYP3A4CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL2902823 | 0.78 | ALDH1A1 (0.64) | KDM5BALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL2906130 | 0.78 | CYP2A13 (0.53) | KDM5BALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL14133155 | 0.77 | ALDH1A1 (0.64) | CYP1A2CYP3A4CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL6670350 | 0.77 | KMT2A (0.53) | CYP1A2CYP3A4CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL6695528 | 0.75 | CYP1A2 (1.00) | KDM5BCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL11157838 | 0.74 | ALDH1A1 (0.67) | CYP1A2CYP3A4CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL6674778 | 0.73 | MAOB (0.44) | KDM5BCYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL6673765 | 0.72 | ALDH1A1 (0.51) | CYP1A2CYP3A4CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL2908931 | 0.72 | ALDH1A1 (0.49) | KDM5BCYP3A4CYP2C9CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004037248-A2 | MODULATION OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS ACTIVITY | CAREX SA (FR) | 2004-05-06 | — | — | WO | claimed |
| WO-2004037248-A2 | MODULATION OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS ACTIVITY | CAREX SA (FR) | 2004-05-06 | — | — | WO | disclosed |