Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.51 |
| ▸ | MEN1 | O00255 | 9/20 | 0.51 |
| ▸ | MAPT | P10636 | 7/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | MITF | O75030 | 1/20 | 0.51 |
| ▸ | UBE2N | P61088 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6674164 | 0.84 | ALDH1A1 (0.48) | ALDH1A1KMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL6678055 | 0.83 | ALDH1A1 (0.54) | ALDH1A1KMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL14133155 | 0.80 | ALDH1A1 (0.64) | ALDH1A1KMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL6670350 | 0.80 | KMT2A (0.53) | ALDH1A1KMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL11157838 | 0.77 | ALDH1A1 (0.67) | ALDH1A1KMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL6682346 | 0.77 | KDM4E (0.49) | ALDH1A1KMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL6673810 | 0.76 | MEN1 (0.56) | ALDH1A1KMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL6688421 | 0.75 | ALDH1A1 (0.70) | ALDH1A1KMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL11960241 | 0.74 | ALDH1A1 (0.55) | ALDH1A1KMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL6674161 | 0.74 | KMT2A (0.47) | ALDH1A1KMT2AMEN1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004037248-A2 | MODULATION OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS ACTIVITY | CAREX SA (FR) | 2004-05-06 | — | — | WO | disclosed |