Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6673044 | 0.86 | ALDH1A1 (0.61) | ALDH1A1GAAHPGDKDM4EGLA | |
| SCHEMBL7845995 | 0.83 | ALDH1A1 (0.49) | ALDH1A1GAAHPGDKDM4EGLA | |
| SCHEMBL6667514 | 0.83 | GAA (0.49) | ALDH1A1GAAHPGDKDM4EGLA | |
| SCHEMBL6670295 | 0.82 | GAA (0.47) | ALDH1A1GAAHPGDKDM4EGLA | |
| SCHEMBL7834064 | 0.80 | GAA (0.51) | ALDH1A1GAAHPGDKDM4EGLA | |
| SCHEMBL7845846 | 0.80 | GAA (0.51) | ALDH1A1GAAHPGDKDM4EGLA | |
| SCHEMBL7834749 | 0.76 | GAA (0.48) | ALDH1A1GAAHPGDKDM4EGLA | |
| SCHEMBL7843626 | 0.76 | GAA (0.47) | ALDH1A1GAAHPGDKDM4EGLA | |
| SCHEMBL6959107 | 0.75 | ALDH1A1 (0.47) | ALDH1A1GAAHPGDKDM4EGLA | |
| SCHEMBL6984758 | 0.75 | ALDH1A1 (0.47) | ALDH1A1GAAHPGDKDM4EGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004019932-A1 | METHOD OF PREVENTING OR TREATING ATHEROSCLEROSIS OR RESTENOSIS | PHARMACIA & UPJOHN COMPANY (US) | 2004-03-11 | — | — | WO | claimed |
| WO-2004019932-A1 | METHOD OF PREVENTING OR TREATING ATHEROSCLEROSIS OR RESTENOSIS | PHARMACIA & UPJOHN COMPANY (US) | 2004-03-11 | — | — | WO | disclosed |