Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | HPGD | P15428 | 4/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | GLA | P06280 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | POLA1 | P09884 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6959107 | 0.88 | ALDH1A1 (0.47) | ALDH1A1HPGDKDM4EGAAGLA | |
| SCHEMBL6984758 | 0.88 | ALDH1A1 (0.47) | ALDH1A1HPGDKDM4EGAAGLA | |
| SCHEMBL7845995 | 0.86 | ALDH1A1 (0.49) | ALDH1A1HPGDKDM4EGAAGLA | |
| SCHEMBL6667514 | 0.86 | GAA (0.49) | ALDH1A1HPGDKDM4EGAAGLA | |
| SCHEMBL6667428 | 0.86 | ALDH1A1 (0.51) | ALDH1A1HPGDKDM4EGAAGLA | |
| SCHEMBL6673045 | 0.86 | ALDH1A1 (0.47) | ALDH1A1HPGDKDM4EGAAGLA | |
| SCHEMBL7841512 | 0.86 | ALDH1A1 (0.46) | ALDH1A1HPGDKDM4EGAAGLA | |
| SCHEMBL7843880 | 0.85 | ALDH1A1 (0.45) | ALDH1A1HPGDKDM4EGAAGLA | |
| SCHEMBL7199782 | 0.85 | ALDH1A1 (0.45) | ALDH1A1HPGDKDM4EGAAGLA | |
| SCHEMBL6670295 | 0.85 | GAA (0.47) | ALDH1A1HPGDKDM4EGAAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004019932-A1 | METHOD OF PREVENTING OR TREATING ATHEROSCLEROSIS OR RESTENOSIS | PHARMACIA & UPJOHN COMPANY (US) | 2004-03-11 | — | — | WO | claimed |