Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | CTSB | P07858 | 1/20 | 0.50 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.48 |
| ▸ | AKR1C4 | P17516 | 2/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.47 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.46 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL57166 | 0.82 | TDP1 (1.00) | TDP1ALDH1A1CTSBGPR35GAA | |
| SCHEMBL29475175 | 0.82 | TDP1 (1.00) | TDP1ALDH1A1CTSBGPR35GAA | |
| SCHEMBL10879332 | 0.81 | TDP1 (0.67) | TDP1ALDH1A1CTSBGPR35AKR1C4 | |
| SCHEMBL11147829 | 0.81 | TDP1 (0.60) | TDP1ALDH1A1GAAMEN1KMT2A | |
| SCHEMBL728448 | 0.80 | MEN1 (0.61) | TDP1ALDH1A1GPR35GAAMEN1 | |
| Methyl Alcohol SCHEMBL28304524 | 0.80 | TDP1 (0.86) | TDP1ALDH1A1CTSBGPR35GAA | |
| SCHEMBL28093598 | 0.80 | TDP1 (0.95) | TDP1ALDH1A1CTSBGPR35GAA | |
| SCHEMBL1396225 | 0.79 | GPR35 (0.58) | TDP1ALDH1A1GPR35GAAMEN1 | |
| SCHEMBL9062960 | 0.79 | MEN1 (0.59) | TDP1ALDH1A1GPR35GAAMEN1 | |
| Ammonia Solution, Strong SCHEMBL2832169 | 0.79 | MEN1 (0.59) | TDP1ALDH1A1GPR35GAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004043417-A2 | COMPOSITION FOR DYEING KERATIN FIBRES CONTAINING A DYE PRECURSOR AND AN ENZYME WITH NITROREDUCTASE ACTIVITY | L'OREAL (FR) | 2004-05-27 | — | — | WO | claimed |
| WO-2004043417-A2 | COMPOSITION FOR DYEING KERATIN FIBRES CONTAINING A DYE PRECURSOR AND AN ENZYME WITH NITROREDUCTASE ACTIVITY | L'OREAL (FR) | 2004-05-27 | — | — | WO | disclosed |