Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 15/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 15/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 15/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 15/20 | 0.47 |
| ▸ | PNP | P00491 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.42 |
| ▸ | CSF1R | P07333 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6674809 | 0.96 | PDE4A (0.48) | PDE4APDE4BPDE4CPDE4DPNP | |
| SCHEMBL6672888 | 0.89 | PDE4A (0.62) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6672884 | 0.89 | PDE4A (0.47) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6675826 | 0.83 | PDE4A (0.55) | PDE4APDE4BPDE4CPDE4DPNP | |
| SCHEMBL6672649 | 0.82 | PDE4A (0.66) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7740525 | 0.82 | PDE4A (0.61) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6673308 | 0.81 | SIRT2 (0.45) | MAPK1HSD17B10KDM4EALDH1A1LMNA | |
| SCHEMBL6677681 | 0.79 | MET (0.46) | PDE4APDE4BPDE4CPDE4DPNP | |
| SCHEMBL6674993 | 0.77 | ALDH1A1 (0.45) | MAPK1HSD17B10KDM4EALDH1A1LMNA | |
| SCHEMBL7491119 | 0.75 | PDE4A (0.47) | PDE4APDE4BPDE4CPDE4DPNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1202628-A4 | NOVEL HYPOXANTHINE AND THIOHYPOXANTHINE COMPOUNDS | EURO CELTIQUE SA (LU) | 2002-10-30 | — | — | EP | claimed |
| EP-1202628-A1 | NOVEL HYPOXANTHINE AND THIOHYPOXANTHINE COMPOUNDS | Euro-Celtique S.A. (LU) | 2002-05-08 | — | — | EP | claimed |
| WO-2001011967-A1 | NOVEL HYPOXANTHINE AND THIOHYPOXANTHINE COMPOUNDS | EURO-CELTIQUE S.A. (LU) | 2001-02-22 | — | — | WO | claimed |
| EP-1202628-B1 | NOVEL HYPOXANTHINE AND THIOHYPOXANTHINE COMPOUNDS | EURO CELTIQUE SA (LU) | 2004-10-13 | — | — | EP | disclosed |
| EP-1045849-B1 | PURINE DERIVATIVES HAVING PHOSPHODIESTERASE IV INHIBITION ACTIVITY | EURO CELTIQUE SA (LU) | 2003-07-02 | — | — | EP | disclosed |
| EP-1202628-A4 | NOVEL HYPOXANTHINE AND THIOHYPOXANTHINE COMPOUNDS | EURO CELTIQUE SA (LU) | 2002-10-30 | — | — | EP | disclosed |
| EP-1202628-A1 | NOVEL HYPOXANTHINE AND THIOHYPOXANTHINE COMPOUNDS | Euro-Celtique S.A. (LU) | 2002-05-08 | — | — | EP | disclosed |
| EP-1045849-A4 | PURINE DERIVATIVES HAVING PHOSPHODIESTERASE IV INHIBITION ACTIVITY | EURO CELTIQUE SA (LU) | 2001-10-31 | — | — | EP | disclosed |
| US-6228859-B1 | ANTIASTHMATIC, ANTIINFLAMMATORY, ANTIALLERGEN AND ANTIDEPRESSANT AGENTS | EURO-CELTIQUE S.A. (LU) | 2001-05-08 | — | — | US | disclosed |
| WO-2001011967-A1 | NOVEL HYPOXANTHINE AND THIOHYPOXANTHINE COMPOUNDS | EURO-CELTIQUE S.A. (LU) | 2001-02-22 | — | — | WO | disclosed |
| EP-1045849-A1 | PURINE DERIVATIVES HAVING PHOSPHODIESTERASE IV INHIBITION ACTIVITY | Euro-Celtique S.A. (LU) | 2000-10-25 | — | — | EP | disclosed |
| WO-1999031102-A1 | PURINE DERIVATIVES HAVING PHOSPHODIESTERASE IV INHIBITION ACTIVITY | EURO-CELTIQUE, S.A. (LU) | 1999-06-24 | — | — | WO | disclosed |