Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACR | P10323 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.36 |
| ▸ | CFTR | P13569 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.34 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.34 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.34 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.34 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.34 |
| ▸ | LGALS7; LGALS7B | P47929 | 1/20 | 0.34 |
| ▸ | MAP3K7 | O43318 | 2/20 | 0.34 |
| ▸ | TAB1 | Q15750 | 2/20 | 0.34 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3010858 | 0.83 | HPGD (0.36) | HPGDRAB9A | |
| SCHEMBL3010041 | 0.81 | HPGD (0.37) | HPGDRAB9A | |
| SCHEMBL1437259 | 0.80 | CNR1 (0.41) | PARP1 | |
| SCHEMBL1437208 | 0.77 | EGLN1 (0.35) | HPGD | |
| SCHEMBL2995161 | 0.77 | POLB (0.41) | HPGDRAB9A | |
| SCHEMBL3008343 | 0.76 | SMN1; SMN2 (0.41) | ADORA2AADORA1HPGDRAB9A | |
| SCHEMBL1437230 | 0.76 | CNR1 (0.40) | HPGD | |
| SCHEMBL5806551 | 0.75 | ALDH1A1 (0.33) | HPGDRAB9A | |
| SCHEMBL14587447 | 0.75 | CA12 (0.40) | RAB9A | |
| SCHEMBL31634153 | 0.75 | EGLN1 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1478624-A1 | CHEMICAL COMPOUNDS | AstraZeneca AB (SE) | 2004-11-24 | — | — | EP | disclosed |
| WO-2003068743-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2003-08-21 | — | — | WO | disclosed |