Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 4/20 | 0.40 |
| ▸ | GBA1 | P04062 | 1/20 | 0.37 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 7/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 7/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 7/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 7/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.32 |
| ▸ | MGLL | Q99685 | 2/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6673867 | 0.99 | ADORA2B (0.42) | ADORA2BGBA1HPRT1PDE4APDE4B | |
| SCHEMBL6673897 | 0.96 | PDE4A (0.38) | ADORA2BHPRT1PDE4APDE4BPDE4C | |
| SCHEMBL6676174 | 0.90 | HPRT1 (0.38) | ADORA2BHPRT1PDE4APDE4BPDE4C | |
| SCHEMBL6679178 | 0.81 | PDE2A (0.38) | ADORA2BHPRT1PDE4APDE4BPDE4C | |
| SCHEMBL6674159 | 0.78 | GDA (0.32) | ADORA2BHPRT1ADORA2AGDA | |
| SCHEMBL6675407 | 0.77 | XDH (0.36) | ADORA2BPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6672658 | 0.76 | XDH (0.37) | ADORA2BPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6672677 | 0.76 | XDH (0.34) | ADORA2BPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6674432 | 0.76 | GDA (0.38) | ADORA2BHPRT1PDE4APDE4BPDE4C | |
| SCHEMBL6675393 | 0.72 | PNP (0.40) | ADORA2BPDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1202628-B1 | NOVEL HYPOXANTHINE AND THIOHYPOXANTHINE COMPOUNDS | EURO CELTIQUE SA (LU) | 2004-10-13 | — | — | EP | claimed |
| EP-1202628-A4 | NOVEL HYPOXANTHINE AND THIOHYPOXANTHINE COMPOUNDS | EURO CELTIQUE SA (LU) | 2002-10-30 | — | — | EP | claimed |
| EP-1202628-A1 | NOVEL HYPOXANTHINE AND THIOHYPOXANTHINE COMPOUNDS | Euro-Celtique S.A. (LU) | 2002-05-08 | — | — | EP | claimed |
| WO-2001011967-A1 | NOVEL HYPOXANTHINE AND THIOHYPOXANTHINE COMPOUNDS | EURO-CELTIQUE S.A. (LU) | 2001-02-22 | — | — | WO | claimed |
| EP-1202628-B1 | NOVEL HYPOXANTHINE AND THIOHYPOXANTHINE COMPOUNDS | EURO CELTIQUE SA (LU) | 2004-10-13 | — | — | EP | disclosed |
| EP-1202628-A4 | NOVEL HYPOXANTHINE AND THIOHYPOXANTHINE COMPOUNDS | EURO CELTIQUE SA (LU) | 2002-10-30 | — | — | EP | disclosed |
| EP-1202628-A1 | NOVEL HYPOXANTHINE AND THIOHYPOXANTHINE COMPOUNDS | Euro-Celtique S.A. (LU) | 2002-05-08 | — | — | EP | disclosed |
| WO-2001011967-A1 | NOVEL HYPOXANTHINE AND THIOHYPOXANTHINE COMPOUNDS | EURO-CELTIQUE S.A. (LU) | 2001-02-22 | — | — | WO | disclosed |