Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 8/20 | 0.44 |
| ▸ | MAOB | P27338 | 5/20 | 0.34 |
| ▸ | CALML3 | P27482 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | SDHA | P31040 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3045011 | 1.00 | MAOA (0.44) | MAOAMAOBCALML3LMNAPTGS1 | |
| SCHEMBL3043154 | 0.88 | MAOA (0.42) | MAOAMAOBCALML3LMNAPTGS1 | |
| SCHEMBL3041102 | 0.88 | MAOA (0.44) | MAOAMAOBCALML3LMNAPTGS1 | |
| SCHEMBL3040902 | 0.86 | MAOA (0.42) | MAOAMAOBCALML3LMNAPTGS1 | |
| SCHEMBL3044279 | 0.86 | MAOA (0.42) | MAOAMAOBCALML3LMNAPTGS1 | |
| SCHEMBL5766092 | 0.79 | ALDH1A1 (0.46) | MAOALMNATSHR | |
| SCHEMBL3048745 | 0.78 | MAOA (0.51) | MAOAMAOBCALML3LMNAPTGS1 | |
| SCHEMBL3048749 | 0.78 | MAOA (0.51) | MAOAMAOBCALML3LMNAPTGS1 | |
| SCHEMBL3033082 | 0.77 | MAOA (0.52) | MAOAMAOBCALML3LMNAPTGS1 | |
| SCHEMBL3042626 | 0.77 | MAOA (0.52) | MAOAMAOBCALML3LMNAPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1478629-A1 | N-ARYL-2-OXAZOLIDINONE-5-CARBOXAMIDES AND THEIR DERIVATIVES AND THEIR USE AS ANTIBACTERIALS | PHARMACIA & UPJOHN COMPANY (US) | 2004-11-24 | — | — | EP | disclosed |
| WO-2003072553-A1 | N-ARYL-2-OXAZOLIDINONE-5-CARBOXAMIDES AND THEIR DERIVATES AND THEIR USE AS ANTIBACTERIALS | PHARMACIA & UPJOHN COMPANY (US) | 2003-09-04 | — | — | WO | disclosed |