Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB2 known ✓ | P30411 | 1/20 | 0.31 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hexane SCHEMBL29140428 | 0.84 | TSHR (0.32) | — | |
| Heptane SCHEMBL28498778 | 0.82 | TSHR (0.36) | — | |
| SCHEMBL27603050 | 0.82 | TSHR (0.36) | — | |
| Butane SCHEMBL28466965 | 0.80 | — | — | |
| Fluoride SCHEMBL29154662 | 0.74 | — | — | |
| SCHEMBL9501078 | 0.74 | — | — | |
| SCHEMBL20751 | 0.74 | — | — | |
| Alcohol SCHEMBL2359135 | 0.73 | ALDH1A1 (0.30) | — | |
| SCHEMBL18116181 | 0.72 | — | — | |
| Cyclopropane SCHEMBL9251557 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1081272-B1 | Fiber treatment composition containing amine, polyol, amide-functional siloxanes | DOW CORNING (US) | 2004-10-13 | — | — | EP | disclosed |
| US-6255429-B1 | FIBER TREATMENT COMPOSITIONS PROVIDING GOOD HAND, RESISTANCE TO YELLOWING, AND HYDROPHILICITY | DOW CORNING CORPORATION | 2001-07-03 | — | — | US | disclosed |
| EP-1081272-A1 | Fiber treatment composition containing amine, polyol, amide-functional siloxanes | DOW CORNING CORPORATION (US) | 2001-03-07 | — | — | EP | disclosed |
| US-6136215-A | FOR IMPARTING NATURAL AND SYNTHETIC TEXTILE FILBERS WITH HYDROPILICITY AND YELLOWING RESISTANCE AND HAND(FEEL) | DOW CORNING CORPORATION (US) | 2000-10-24 | — | — | US | disclosed |