Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTTP | P55157 | 16/20 | 0.77 |
| ▸ | APOB | P04114 | 15/20 | 0.77 |
| ▸ | SMO | Q99835 | 7/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6678706 | 1.00 | MTTP (0.77) | MTTPAPOBSMO | |
| SCHEMBL6673949 | 0.91 | MTTP (0.63) | MTTPAPOBSMO | |
| SCHEMBL4785948 | 0.87 | MTTP (1.00) | MTTPAPOBSMO | |
| SCHEMBL7038523 | 0.87 | MTTP (1.00) | MTTPAPOBSMO | |
| SCHEMBL10205353 | 0.87 | MTTP (1.00) | MTTPAPOBSMO | |
| SCHEMBL6196022 | 0.80 | MTTP (0.87) | MTTPAPOBSMO | |
| SCHEMBL13591624 | 0.79 | MTTP (0.85) | MTTPAPOBSMO | |
| SCHEMBL5961560 | 0.78 | SMO (0.85) | MTTPAPOBSMO | |
| SCHEMBL13591625 | 0.77 | APOB (0.73) | MTTPAPOBSMO | |
| SCHEMBL7764346 | 0.76 | APOB (1.00) | MTTPAPOBSMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1465613-A2 | COMBINATION OF MTP INHIBITORS OR APOB SECRETION INHIBITORS WITH FIBRATES FOR USE AS DRUGS | Boehringer Ingelheim Pharma GmbH & Co. KG (DE) | 2004-10-13 | — | — | EP | claimed |
| WO-2003057205-A2 | COMBINATION OF MTP INHIBITORS OR APOB SECRETION INHIBITORS WITH FIBRATES FOR USE AS DRUGS | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2003-07-17 | — | — | WO | claimed |
| EP-1465613-A2 | COMBINATION OF MTP INHIBITORS OR APOB SECRETION INHIBITORS WITH FIBRATES FOR USE AS DRUGS | Boehringer Ingelheim Pharma GmbH & Co. KG (DE) | 2004-10-13 | — | — | EP | disclosed |
| WO-2003057205-A2 | COMBINATION OF MTP INHIBITORS OR APOB SECRETION INHIBITORS WITH FIBRATES FOR USE AS DRUGS | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2003-07-17 | — | — | WO | disclosed |