SCHEMBL667466

SCHEMBL667466

O=C(O)c1nc([N+](=O)[O-])c([N+](=O)[O-])[nH]1

nearest known ligand 0.38

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.38
KDM4E B2RXH2 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2C9 P11712 1/20 0.34
PTPRB P23467 1/20 0.34
HSD17B10 Q99714 1/20 0.34
MAPT P10636 2/20 0.34
APEX1 P27695 1/20 0.32
KMT2A Q03164 1/20 0.32
PIN1 Q13526 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15388820 0.85 CGAS (0.34) MAPT
1,2,4-Triazole SCHEMBL15388432 0.84
SCHEMBL15388696 0.81 KDM4E (0.32) LMNAKDM4EMAPT
SCHEMBL5310322 0.79 LMNA (0.37) LMNAKDM4ECYP3A4CYP2C9PTPRB
SCHEMBL5310539 0.75 LMNA (0.34) LMNAKDM4ECYP3A4CYP2C9PTPRB
SCHEMBL28879734 0.74 MAPT (0.33) KDM4EMAPTKMT2A
SCHEMBL4021901 0.73 KDM4E (0.34) LMNAKDM4EMAPT
SCHEMBL5348550 0.73 GALR3 (0.33) MAPTKMT2A
SCHEMBL11899744 0.73 GALR3 (0.33) MAPTKMT2A
Water SCHEMBL9252225 0.71 GALR3 (0.33) MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230059863-A1 SEPARATION OF RARE EARTH METALS UNIV BELFAST (GB) 2023-02-23 US claimed
US-11396684-B2 Extracting rare earth metal from acidic solution by contacting with ionic liquid composition THE QUEEN'S UNIVERSITY OF BELFAST (GB) 2022-07-26 US claimed
EP-3555325-B1 SEPARATION OF RARE EARTH METALS UNIV BELFAST (GB) 2021-06-30 EP claimed
US-10626335-B2 Process for removing metals from hydrocarbons PETROLIAM NASIONAL BERHAD (PETRONAS) (MY) 2020-04-21 US claimed
US-20200080169-A1 SEPARATION OF RARE EARTH METALS THE QUEEN'S UNIVERSITY OF BELFAST (GB) 2020-03-12 US claimed
EP-2417225-B1 PROCESS FOR REMOVING MERCURY FROM HYDROCARBONS PETROLIAM NASIONAL BERHAD PETRONAS (MY) 2020-03-11 EP claimed
EP-3555325-A1 SEPARATION OF RARE EARTH METALS The Queen's University Of Belfast (GB) 2019-10-23 EP claimed
US-10138432-B2 Process for removing metals from hydrocarbons THE QUEEN'S UNIVERSITY OF BELFAST (GB) 2018-11-27 US claimed
WO-2018109483-A1 SEPARATION OF RARE EARTH METALS THE QUEEN'S UNIVERSITY OF BELFAST (GB) 2018-06-21 WO claimed
US-20170037323-A1 PROCESS FOR REMOVING METALS FROM HYDROCARBONS PETROLIAM NASIONAL BERHAD (PETRONAS) (MY) 2017-02-09 US claimed
EP-2620422-B1 N2O-based, ionic monopropellants for space propulsion CENTRE NAT ETD SPATIALES (FR) 2014-04-23 EP claimed
US-20140001100-A1 PROCESS FOR REMOVING METALS FROM HYDROCARBONS THE QUEEN'S UNIVERSITY OF BELFAST (GB) 2014-01-02 US claimed
EP-2625249-A2 PROCESS FOR REMOVING METALS FROM HYDROCARBONS The Queen's University of Belfast (GB) 2013-08-14 EP claimed
EP-2620422-A1 N2O-based, ionic monopropellants for space propulsion CENTRE NATIONAL D'ETUDES SPATIALES (FR) 2013-07-31 EP claimed
US-20120234687-A1 SOLDERING PROCESS USING ELECTRODEPOSITED INDIUM AND/OR GALLIUM, AND ARTICLE COMPRISING AN INTERMEDIATE LAYER WITH INDIUM AND/OR GALLIUM ASTRON ADVANCED MATERIALS LIMITED (GB) 2012-09-20 US claimed
EP-2475496-A1 SOLDERING PROCESS USING ELECTRODEPOSITED INDIUM AND/OR GALLIUM, AND ARTICLE COMPRISING AN INTERMEDIATE LAYER WITH INDIUM AND/OR GALLIUM Astron Advanced Materials Limited (GB) 2012-07-18 EP claimed
US-20120121485-A1 PROCESS FOR REMOVING METALS FROM HYDROCARBONS PETROLIAM NASIONAL BERHAD (PETRONAS) (MY) 2012-05-17 US claimed
WO-2012046057-A2 PROCESS FOR REMOVING METALS FROM HYDROCARBONS THE QUEEN'S UNIVERSITY OF BELFAST (GB) 2012-04-12 WO claimed
WO-2010116165-A2 PROCESS FOR REMOVING METALS FROM HYDROCARBONS PETROLIAM NASIONAL BERHAD (PETRONAS) (MY) 2010-10-14 WO claimed
US-5395945-A Salt formation, neutralization THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY (US) 1995-03-07 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10626335-B2 Process for removing metals from hydrocarbons SHH, AHR, HTT LMNA 1042/4885KDM4E 1506/4885CYP3A4 1228/4885
US-20120121485-A1 PROCESS FOR REMOVING METALS FROM HYDROCARBONS SHH, AHR, HTT LMNA 1042/4885KDM4E 1506/4885CYP3A4 1228/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.