Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.34 |
| ▸ | FBP1 | P09467 | 5/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | PTPRB | P23467 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4021901 | 0.87 | KDM4E (0.34) | LMNAHCAR2FBP1MAPTKDM4E | |
| SCHEMBL5310322 | 0.77 | LMNA (0.37) | LMNAMAPTPIN1KDM4ECYP3A4 | |
| SCHEMBL667466 | 0.75 | LMNA (0.38) | LMNAMAPTPIN1KDM4ECYP3A4 | |
| SCHEMBL2822746 | 0.73 | HCAR2 (0.43) | LMNAHCAR2PIN1KDM4ECYP3A4 | |
| SCHEMBL2823071 | 0.72 | HSD17B10 (0.46) | LMNAHCAR2PIN1KDM4ECYP3A4 | |
| SCHEMBL2822836 | 0.72 | LMNA (0.38) | LMNAHCAR2PIN1KDM4ECYP3A4 | |
| Hydrochloric Acid SCHEMBL2824409 | 0.70 | HSD17B10 (0.44) | LMNAHCAR2PIN1KDM4ECYP3A4 | |
| SCHEMBL11499636 | 0.70 | HCAR2 (0.45) | LMNAHCAR2FBP1MAPTCYP2C19 | |
| SCHEMBL2824744 | 0.69 | LMNA (0.40) | LMNAHCAR2MAPTPIN1KDM4E | |
| SCHEMBL2822253 | 0.68 | HCAR2 (0.38) | LMNAHCAR2PIN1KDM4ECYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007045096-A1 | OLIGOHETEROAROMATIC LUMINISCENT ASSEMBLIES AS HIGH-AFFINITY DNA SEQUENCE-DIRECTED LIGANDS | UNIVERSITY OF SASKATCHEWAN (CA) | 2007-04-26 | — | — | WO | disclosed |