Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.40 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.39 |
| ▸ | FADS1 | O60427 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6681868 | 0.99 | KDM4E (0.40) | MEN1KMT2AKDM4EGRIN2DGRIN3B | |
| SCHEMBL5078290 | 0.80 | MEN1 (0.46) | MEN1KMT2AKDM4EGRIN2DGRIN3B | |
| SCHEMBL27495551 | 0.78 | FADS1 (0.40) | MEN1KMT2AKDM4EGRIN2DGRIN3B | |
| SCHEMBL6679305 | 0.77 | KDM4E (0.39) | MEN1KMT2AKDM4EGRIN2DGRIN3B | |
| Hydrochloric Acid SCHEMBL27564541 | 0.77 | FADS1 (0.39) | MEN1KMT2AKDM4EGRIN2DGRIN3B | |
| Hydrochloric Acid SCHEMBL6675888 | 0.76 | KDM4E (0.39) | MEN1KMT2AKDM4EGRIN2DGRIN3B | |
| SCHEMBL6675005 | 0.76 | KMT2A (0.41) | MEN1KMT2AGRIN2DGRIN3BGRIN1 | |
| SCHEMBL6677091 | 0.76 | ENPP2 (0.44) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL4981820 | 0.75 | HDAC4 (0.49) | MEN1KMT2AKDM4EGRIN2DGRIN3B | |
| Hydrochloric Acid SCHEMBL6676190 | 0.75 | KMT2A (0.40) | MEN1KMT2AGRIN2DGRIN3BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798292-B1 | ANILINE DERIVATIVES HAVING NITROGEN MONOXIDE SYNTHASE INHIBITORY ACTIVITY | CHUGAI SEIYAKUKABUSHIKI KAISHA (JP) | 2004-11-03 | — | — | EP | claimed |