Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | MGAM | O43451 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | SI | P14410 | 2/20 | 0.47 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 5/20 | 0.44 |
| ▸ | PPARA | Q07869 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6671105 | 0.97 | KMO (0.54) | KMOKMT2ABCL2L1MCL1MGAM | |
| SCHEMBL6674727 | 0.92 | KMT2A (0.47) | KMOKMT2ABCL2L1MCL1MGAM | |
| SCHEMBL6662270 | 0.92 | KMT2A (0.48) | KMOKMT2ABCL2L1MCL1MGAM | |
| SCHEMBL3104154 | 0.89 | KMT2A (0.68) | KMOKMT2ABCL2L1MCL1ALDH1A1 | |
| SCHEMBL16284888 | 0.85 | NPC1 (0.60) | KMOKMT2ANPC1RAB9APPARG | |
| SCHEMBL3101828 | 0.85 | NPC1 (0.60) | KMOKMT2ANPC1RAB9APPARG | |
| SCHEMBL6672877 | 0.85 | NPC1 (0.60) | KMOKMT2ANPC1RAB9APPARG | |
| SCHEMBL16284887 | 0.85 | NPC1 (0.60) | KMOKMT2ANPC1RAB9APPARG | |
| SCHEMBL3104413 | 0.84 | KMO (0.68) | KMOPPARGPPARA | |
| SCHEMBL9554501 | 0.82 | KMO (0.72) | KMOBCL2L1MCL1PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1458412-A1 | PHARMACEUTICAL COMPOSITION COMPRISING AN ALPHA-GLUCOSIDASE INHIBITOR AND A 4-OXOBUTANOIC ACID, AND THE USE THEREOF FOR TREATING DIABETES | MERCK PATENT GmbH (DE) | 2004-09-22 | — | — | EP | claimed |
| WO-2003055523-A1 | PHARMACEUTICAL COMPOSITION COMPRISING AN ALPHA-GLUCOSIDASE INHIBITOR AND A 4-OXOBUTANOIC ACID, AND THE USE THEREOF FOR TREATING DIABETES | MERCK PATENT GMBH (DE) | 2003-07-10 | — | — | WO | claimed |