Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 3/20 | 0.37 |
| ▸ | HTR1D | P28221 | 2/20 | 0.37 |
| ▸ | HTR6 | P50406 | 2/20 | 0.37 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.37 |
| ▸ | BTK | Q06187 | 2/20 | 0.37 |
| ▸ | MRGPRX2 | Q96LB1 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | HTR1B | P28222 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 5/20 | 0.36 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6311156 | 0.87 | HSD17B10 (0.38) | HTR3AHTR1DHTR6TMEM97MAPK8 | |
| SCHEMBL6318849 | 0.83 | CASP1 (0.38) | HTR3AHTR1DHTR6TMEM97MAPK8 | |
| SCHEMBL5440186 | 0.82 | KDM1A (0.44) | HTR3AHTR1DHTR6TMEM97MAPK8 | |
| SCHEMBL6392201 | 0.81 | MAPK8 (0.40) | HTR3AHTR1DHTR6TMEM97MAPK8 | |
| SCHEMBL6312402 | 0.80 | ALDH1A1 (0.37) | HTR3AHTR1DHTR6TMEM97MAPK8 | |
| SCHEMBL6311058 | 0.80 | HRH3 (0.36) | HTR3AHTR1DHTR6TMEM97MAPK8 | |
| SCHEMBL5446972 | 0.78 | MAPK8 (0.42) | HTR3AHTR1DHTR6TMEM97MAPK8 | |
| SCHEMBL5458304 | 0.78 | MAPK8 (0.44) | HTR3AHTR1DHTR6TMEM97MAPK8 | |
| Formic Acid SCHEMBL6310674 | 0.78 | ALDH1A1 (0.46) | MEN1ALDH1A1LMNAKMT2ACYP2C9 | |
| SCHEMBL5442797 | 0.78 | MAPK8 (0.43) | HTR3AHTR1DHTR6TMEM97MAPK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1479681-A1 | IMIDAZO(1,2-a)PYRIDINE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2004-11-24 | — | — | EP | disclosed |