Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6680873 | 0.86 | CYP1A2 (0.43) | ALDH1A1SMN1; SMN2GAANPC1RAB9A | |
| SCHEMBL6676196 | 0.85 | CA9 (0.45) | LOXL2CA9 | |
| Hydrochloric Acid SCHEMBL6676735 | 0.85 | KMT2A (0.44) | ALDH1A1SMN1; SMN2GAANPC1RAB9A | |
| SCHEMBL6677679 | 0.84 | CYP19A1 (0.44) | ALDH1A1SMN1; SMN2GAANPC1RAB9A | |
| SCHEMBL10384268 | 0.82 | MAPT (0.42) | ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL6679466 | 0.82 | KDM1A (0.43) | ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL6677685 | 0.79 | CYP19A1 (0.38) | ALDH1A1SMN1; SMN2GAA | |
| Acetic Acid SCHEMBL6681849 | 0.78 | KDM1A (0.43) | ALDH1A1SMN1; SMN2GAANPC1RAB9A | |
| SCHEMBL10384379 | 0.78 | MEN1 (0.50) | ALDH1A1SMN1; SMN2GAANPC1RAB9A | |
| SCHEMBL10384376 | 0.78 | MEN1 (0.53) | ALDH1A1SMN1; SMN2GAANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798292-B1 | ANILINE DERIVATIVES HAVING NITROGEN MONOXIDE SYNTHASE INHIBITORY ACTIVITY | CHUGAI SEIYAKUKABUSHIKI KAISHA (JP) | 2004-11-03 | — | — | EP | claimed |
| EP-0798292-B1 | ANILINE DERIVATIVES HAVING NITROGEN MONOXIDE SYNTHASE INHIBITORY ACTIVITY | CHUGAI SEIYAKUKABUSHIKI KAISHA (JP) | 2004-11-03 | — | — | EP | disclosed |
| US-6534546-B1 | Guanidine- or isothioureido-N-derived anilines; brain, nervous system, and neurodegenerative disorders | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2003-03-18 | — | — | US | disclosed |
| EP-0798292-A1 | ANILINE DERIVATIVES HAVING NITROGEN MONOXIDE SYNTHASE INHIBITORY ACTIVITY | Chugai Seiyaku Kabushiki Kaisha (JP) | 1997-10-01 | — | — | EP | disclosed |