Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KIT | P10721 | 1/20 | 0.37 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | BAZ1A | Q9NRL2 | 2/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL6681849 | 0.95 | KDM1A (0.43) | KDM1ARCOR1GAASMN1; SMN2ALDH1A1 | |
| SCHEMBL6674882 | 0.82 | CFD (0.43) | GAASMN1; SMN2ALDH1A1 | |
| SCHEMBL10384268 | 0.82 | MAPT (0.42) | KDM1ARCOR1GAASMN1; SMN2ALDH1A1 | |
| SCHEMBL6677679 | 0.81 | CYP19A1 (0.44) | GAASMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL6680873 | 0.80 | CYP1A2 (0.43) | GAASMN1; SMN2ALDH1A1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL6676735 | 0.79 | KMT2A (0.44) | GAASMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL6679400 | 0.78 | KDM1A (0.44) | KDM1ARCOR1GAASMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6677388 | 0.77 | KDM1A (0.43) | KDM1ARCOR1GAASMN1; SMN2ALDH1A1 | |
| SCHEMBL6681975 | 0.77 | AKT1 (0.44) | — | |
| SCHEMBL3728364 | 0.76 | NOS1 (0.50) | KDM1ARCOR1ALDH1A1KITPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798292-B1 | ANILINE DERIVATIVES HAVING NITROGEN MONOXIDE SYNTHASE INHIBITORY ACTIVITY | CHUGAI SEIYAKUKABUSHIKI KAISHA (JP) | 2004-11-03 | — | — | EP | claimed |