Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | DDX3X | O00571 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6676735 | 0.99 | KMT2A (0.44) | CYP1A2CYP3A4PKMALOX15NFKB1 | |
| SCHEMBL6677679 | 0.88 | CYP19A1 (0.44) | PKMMAPK1KMT2AMAPTALDH1A1 | |
| SCHEMBL6674882 | 0.86 | CFD (0.43) | ALDH1A1SMN1; SMN2GAANPC1RAB9A | |
| SCHEMBL6677685 | 0.82 | CYP19A1 (0.38) | PKMKMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL6679466 | 0.80 | KDM1A (0.43) | KMT2AMAPTALDH1A1SMN1; SMN2GAA | |
| SCHEMBL10384268 | 0.80 | MAPT (0.42) | MAPK1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL6676251 | 0.79 | SMN1; SMN2 (0.40) | PKMKMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL6676252 | 0.78 | CYP19A1 (0.38) | KMT2ASMN1; SMN2GAACYP19A1MEN1 | |
| SCHEMBL6679736 | 0.78 | GLS (0.46) | KMT2AMAPTMEN1 | |
| Acetic Acid SCHEMBL6681849 | 0.76 | KDM1A (0.43) | CYP1A2CYP3A4ALOX15KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798292-B1 | ANILINE DERIVATIVES HAVING NITROGEN MONOXIDE SYNTHASE INHIBITORY ACTIVITY | CHUGAI SEIYAKUKABUSHIKI KAISHA (JP) | 2004-11-03 | — | — | EP | claimed |