Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 13/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 11/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.40 |
| ▸ | ITGAV | P06756 | 3/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | CDK4 | P11802 | 1/20 | 0.34 |
| ▸ | CCND1 | P24385 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7438405 | 0.77 | ITGB3 (0.67) | ITGB3ITGA2BROCK2ITGAVROCK1 | |
| SCHEMBL6700351 | 0.70 | ITGB3 (0.55) | ITGB3ITGA2BITGAV | |
| SCHEMBL8019041 | 0.70 | ITGB3 (0.55) | ITGB3ITGA2BITGAV | |
| SCHEMBL6950004 | 0.69 | ITGB3 (0.66) | ITGB3ITGA2BROCK2ITGAV | |
| SCHEMBL6674851 | 0.68 | ITGB3 (0.61) | ITGB3ITGA2BITGAV | |
| SCHEMBL6674848 | 0.68 | ITGB3 (0.61) | ITGB3ITGA2BITGAV | |
| SCHEMBL6947924 | 0.66 | ITGB3 (0.74) | ITGB3ITGA2BITGAV | |
| SCHEMBL6947929 | 0.66 | ITGB3 (0.74) | ITGB3ITGA2BITGAV | |
| SCHEMBL6674305 | 0.66 | ITGB3 (0.69) | ITGB3ITGA2BROCK2ITGAV | |
| SCHEMBL6945833 | 0.65 | ITGB3 (0.72) | ITGB3ITGA2BROCK2ITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1435958-A1 | USE OF PHOSPHORODIESTERASE IV INHIBITORS | MERCK PATENT GmbH (DE) | 2004-07-14 | — | — | EP | disclosed |
| WO-2003032993-A1 | USE OF PHOSPHORODIESTERASE IV INHIBITORS | MERCK PATENT GMBH (DE) | 2003-04-24 | — | — | WO | disclosed |