Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | DAO | P14920 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6392624 | 0.84 | RAB9A (0.53) | MAPTL3MBTL1TDP1LMNASMN1; SMN2 | |
| SCHEMBL6391680 | 0.83 | CYP1A2 (0.43) | MAPTL3MBTL1TDP1LMNASMN1; SMN2 | |
| SCHEMBL6394361 | 0.81 | L3MBTL1 (0.68) | MAPTL3MBTL1TDP1LMNASMN1; SMN2 | |
| SCHEMBL6635668 | 0.77 | RAB9A (0.43) | MAPTL3MBTL1TDP1LMNASMN1; SMN2 | |
| SCHEMBL6638339 | 0.77 | NPC1 (0.42) | MAPTL3MBTL1TDP1LMNASMN1; SMN2 | |
| SCHEMBL6643256 | 0.77 | CYP1A2 (0.48) | MAPTL3MBTL1TDP1LMNASMN1; SMN2 | |
| SCHEMBL8136440 | 0.76 | HTT (0.40) | MAPTL3MBTL1TDP1LMNASMN1; SMN2 | |
| SCHEMBL6638341 | 0.76 | MAPK1 (0.47) | MAPTL3MBTL1TDP1LMNASMN1; SMN2 | |
| SCHEMBL6393377 | 0.76 | KMT2A (0.58) | MAPTL3MBTL1TDP1LMNASMN1; SMN2 | |
| SCHEMBL6640908 | 0.73 | MEN1 (0.44) | TDP1SMN1; SMN2CYP1A2CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1444208-A1 | SUBSTITUTED PYRIMIDINES | Bayer CropScience AG (DE) | 2004-08-11 | — | — | EP | disclosed |
| WO-2003037878-A1 | SUBSTITUTED PYRIMIDINES | BAYER CROPSCIENCE AG (DE) | 2003-05-08 | — | — | WO | disclosed |