SCHEMBL6675403

SCHEMBL6675403

C=CCn1ccn(CC=C)c1=O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.52
CYP1A2 P05177 1/20 0.47
CYP2D6 P10635 1/20 0.47
ADORA2B P29275 3/20 0.41
KMT2A Q03164 3/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
NPSR1 Q6W5P4 1/20 0.36
ADORA2A P29274 2/20 0.36
PDE4A P27815 1/20 0.36
PDE4B Q07343 1/20 0.36
PDE4C Q08493 1/20 0.36
PDE4D Q08499 1/20 0.36
ALDH1A1 P00352 2/20 0.35
CASP3 P42574 1/20 0.35
GAA P10253 2/20 0.35
NPC1 O15118 2/20 0.35
KDM4E B2RXH2 1/20 0.34
GLA P06280 1/20 0.34
HPGD P15428 1/20 0.34
RCE1 Q9Y256 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6028160 0.77 CYP3A4 (0.50) CYP3A4CYP1A2CYP2D6ADORA2BKMT2A
SCHEMBL264020 0.75 CYP3A4 (0.39) CYP3A4CYP1A2CYP2D6ADORA2BKMT2A
SCHEMBL2467760 0.74 CYP3A4 (0.35) CYP3A4CYP1A2CYP2D6ADORA2BKMT2A
Hydrochloric Acid SCHEMBL14246418 0.72 CYP3A4 (0.33) CYP3A4CYP1A2CYP2D6
SCHEMBL4615672 0.70
SCHEMBL1381419 0.70 POLB (0.46) KMT2ANPSR1ALDH1A1CASP3GAA
SCHEMBL175260 0.70
SCHEMBL11099967 0.70
SCHEMBL3807230 0.70 ALDH1A1 (0.41) CYP3A4CYP1A2CYP2D6NPSR1ALDH1A1
SCHEMBL9293162 0.69 CYP3A4 (0.37) CYP3A4CYP1A2CYP2D6ADORA2BKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1210264-C 1,3-dialkyl-2-imidazolinones and its prepn. MITSUI CHEMICALS INC (JP) 2005-07-13 CN disclosed
EP-1303549-B1 PARTIALLY BRANCHED POLYMERS BASF AG (DE) 2004-10-06 EP disclosed
US-6774198-B2 Partially branched polymers BASF AKTIENGESELLSCHAFT (DE) 2004-08-10 US disclosed
EP-0992497-B1 Manufactoring process for 1,3-Dialkyl-2-imidazolinones MITSUI CHEMICALS INC (JP) 2003-12-17 EP disclosed
EP-1148051-A3 1,3-dialkyl-2-imidazolidinones and a manufacturing process therefor Mitsui Chemicals, Inc. (JP) 2003-10-15 EP disclosed
EP-1148052-A3 1,3-dialkyl-2-imidazolidinones and a manufacturing process therefor Mitsui Chemicals, Inc. (JP) 2003-10-15 EP disclosed
US-20030187166-A1 Partially branched polymers BASF AKTIENGESELLSCHAFT (DE) 2003-10-02 US disclosed
EP-1303549-A2 PARTIALLY BRANCHED POLYMERS BASF AKTIENGESELLSCHAFT (DE) 2003-04-23 EP disclosed
WO-2002006363-A2 PARTIALLY BRANCHED POLYMERS BASF AKTIENGESELLSCHAFT (DE) 2002-01-24 WO disclosed
EP-1148051-A2 1,3-dialkyl-2-imidazolidinones and a manufacturing process therefor Mitsui Chemicals, Inc. (JP) 2001-10-24 EP disclosed
EP-1148052-A2 1,3-dialkyl-2-imidazolidinones and a manufacturing process therefor Mitsui Chemicals, Inc. (JP) 2001-10-24 EP disclosed
CN-1256268-A 1,3-dialkyl-2-imidazolinones and its prepn. MITSUI CHEMICALS INC (JP) 2000-06-14 CN disclosed
EP-0992497-A1 1,3-Dialkyl-2-imidazolidinones and a manufacturing process therefor Mitsui Chemicals, Inc. (JP) 2000-04-12 EP disclosed