Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 6/20 | 0.46 |
| ▸ | PNMT | P11086 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.39 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7236379 | 0.99 | TAAR1 (0.45) | TAAR1PNMTLMNASMN1; SMN2GAA | |
| SCHEMBL6677583 | 0.84 | BACE1 (0.39) | TAAR1LMNAGAABACE1MAPT | |
| Hydrochloric Acid SCHEMBL6677530 | 0.83 | LMNA (0.38) | TAAR1LMNAGAAGLABACE1 | |
| SCHEMBL27515137 | 0.82 | TAAR1 (0.47) | TAAR1PNMTLMNASMN1; SMN2GAA | |
| SCHEMBL6679338 | 0.81 | TAAR1 (0.52) | TAAR1LMNAGLAMAPTMEN1 | |
| Hydrochloric Acid SCHEMBL27544116 | 0.81 | TAAR1 (0.46) | TAAR1PNMTLMNASMN1; SMN2GAA | |
| Hydrochloric Acid SCHEMBL6675033 | 0.80 | TAAR1 (0.54) | TAAR1LMNAGLAMAPTMEN1 | |
| SCHEMBL11841394 | 0.78 | ACACB (0.38) | LMNASMN1; SMN2GAABACE1MAPT | |
| SCHEMBL6676401 | 0.76 | TAAR1 (0.46) | TAAR1BACE1KMT2AKDM4EADRA2A | |
| SCHEMBL6675448 | 0.75 | TAAR1 (0.46) | TAAR1PNMTLMNASMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798292-B1 | ANILINE DERIVATIVES HAVING NITROGEN MONOXIDE SYNTHASE INHIBITORY ACTIVITY | CHUGAI SEIYAKUKABUSHIKI KAISHA (JP) | 2004-11-03 | — | — | EP | claimed |