Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 6/20 | 0.46 |
| ▸ | PNMT | P11086 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PTGIR | P43119 | 1/20 | 0.41 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.39 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | NOS1 | P29475 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | NOS3 | P29474 | 2/20 | 0.36 |
| ▸ | NOS2 | P35228 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6675725 | 0.99 | TAAR1 (0.45) | TAAR1PNMTGLASMN1; SMN2PTGIR | |
| SCHEMBL6677586 | 0.84 | SIGMAR1 (0.43) | TAAR1PTGIRBACE1SIGMAR1NOS1 | |
| Hydrochloric Acid SCHEMBL6677533 | 0.83 | SIGMAR1 (0.43) | TAAR1GLASMN1; SMN2BACE1SIGMAR1 | |
| SCHEMBL6679341 | 0.81 | ATM (0.55) | TAAR1GLAPTGIRKDM4EATM | |
| Hydrochloric Acid SCHEMBL6675035 | 0.80 | ATM (0.54) | TAAR1GLAPTGIRKDM4EATM | |
| SCHEMBL6676406 | 0.76 | ADRA2A (0.54) | TAAR1PTGIRSIGMAR1NOS1NOS3 | |
| SCHEMBL27515137 | 0.76 | TAAR1 (0.47) | TAAR1PNMTGLASMN1; SMN2PDK1 | |
| SCHEMBL6675445 | 0.75 | TAAR1 (0.46) | TAAR1PNMTGLASMN1; SMN2PDK1 | |
| Hydrochloric Acid SCHEMBL27544116 | 0.75 | TAAR1 (0.46) | TAAR1PNMTGLASMN1; SMN2PDK1 | |
| Hydrochloric Acid SCHEMBL6689077 | 0.75 | ADRA2A (0.56) | TAAR1PTGIRSIGMAR1NOS1NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798292-B1 | ANILINE DERIVATIVES HAVING NITROGEN MONOXIDE SYNTHASE INHIBITORY ACTIVITY | CHUGAI SEIYAKUKABUSHIKI KAISHA (JP) | 2004-11-03 | — | — | EP | claimed |