SCHEMBL6675514

SCHEMBL6675514

O=c1c2cc3c(=O)n4c(=O)c3cc2c(=O)n1-c1ccc-4cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.65
CA1 P00915 2/20 0.65
CA2 P00918 2/20 0.65
CA9 Q16790 2/20 0.65
MAPK1 P28482 1/20 0.54
KDM4E B2RXH2 3/20 0.48
POLB P06746 3/20 0.48
GAA P10253 1/20 0.48
MAPT P10636 3/20 0.47
NPSR1 Q6W5P4 2/20 0.47
LMNA P02545 2/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
ESR1 P03372 1/20 0.39
KMT2A Q03164 2/20 0.37
MEN1 O00255 1/20 0.37
PTGES O14684 1/20 0.37
ALOX5 P09917 1/20 0.37
DUSP3 P51452 1/20 0.37
MCL1 Q07820 1/20 0.37
CTDSP1 Q9GZU7 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL760529 0.90 CA12 (0.57) CA12CA1CA2CA9MAPK1
SCHEMBL10014682 0.88 CA12 (0.55) CA12CA1CA2CA9MAPK1
SCHEMBL8310146 0.88 CA12 (0.60) CA12CA1CA2CA9MAPK1
SCHEMBL17878218 0.88 CA12 (0.55) CA12CA1CA2CA9MAPK1
SCHEMBL5535503 0.88 CA12 (0.55) CA12CA1CA2CA9MAPK1
SCHEMBL13310390 0.87 MAPK1 (0.74) CA12CA1CA2CA9MAPK1
SCHEMBL17278347 0.84 CA12 (0.52) CA12CA1CA2CA9MAPK1
SCHEMBL15688835 0.83 CA12 (0.50) CA12CA1CA2CA9MAPK1
SCHEMBL12639215 0.82 LMNA (0.73) CA12CA1CA2CA9KDM4E
SCHEMBL5531699 0.82 CA12 (0.50) CA12CA1CA2CA9MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2004322028-A SURFACE TREATMENT METHOD FOR FILTER, NEEDLE FILTER AND WOVEN FILTER NIPPON FELT CO LTD 2004-11-18 JP disclosed