SCHEMBL5535503

SCHEMBL5535503

O=c1c2cc3c(=O)n(-c4ccc(F)cc4)c(=O)c3cc2c(=O)n1-c1ccc(F)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.55
CA1 P00915 2/20 0.55
CA2 P00918 2/20 0.55
CA9 Q16790 2/20 0.55
POLB P06746 2/20 0.50
L3MBTL1 Q9Y468 1/20 0.47
HPGD P15428 1/20 0.47
MPI P34949 3/20 0.46
PMM2 O15305 2/20 0.46
APOBEC3G Q9HC16 2/20 0.46
METAP2 P50579 1/20 0.46
G6PD P11413 1/20 0.46
MGLL Q99685 1/20 0.45
MAPK1 P28482 1/20 0.45
KDM4E B2RXH2 2/20 0.45
GSK3A P49840 1/20 0.44
GSK3B P49841 1/20 0.44
MEN1 O00255 1/20 0.42
ALDH1A1 P00352 1/20 0.42
KMT2A Q03164 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25095011 0.89 HPGD (0.47) CA12CA1CA2CA9POLB
SCHEMBL6675514 0.88 CA12 (0.65) CA12CA1CA2CA9POLB
SCHEMBL12660985 0.81 MGLL (0.48) POLBL3MBTL1HPGDMPIPMM2
SCHEMBL760529 0.79 CA12 (0.57) CA12CA1CA2CA9POLB
SCHEMBL10014682 0.77 CA12 (0.55) CA12CA1CA2CA9POLB
SCHEMBL17878218 0.77 CA12 (0.55) CA12CA1CA2CA9POLB
SCHEMBL8310146 0.77 CA12 (0.60) CA12CA1CA2CA9POLB
SCHEMBL5531699 0.77 CA12 (0.50) CA12CA1CA2CA9MPI
SCHEMBL13310390 0.76 MAPK1 (0.74) CA12CA1CA2CA9POLB
SCHEMBL17537368 0.75 GSK3A (0.55) POLBL3MBTL1HPGDMPIPMM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8168327-B2 Imide derivative, material for organic electroluminescent device and organic electroluminescent device using the same IDEMITSU KOSAN CO., LTD. (JP) 2012-05-01 US disclosed
US-8168327-B2 Imide derivative, material for organic electroluminescent device and organic electroluminescent device using the same IDEMITSU KOSAN CO., LTD. (JP) 2012-05-01 US disclosed
US-20070160905-A1 NOVEL IMIDE DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENT DEVICE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2007-07-12 US disclosed
US-20070160905-A1 NOVEL IMIDE DERIVATIVE, MATERIAL FOR ORGANIC ELECTROLUMINESCENT DEVICE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2007-07-12 US disclosed