Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 15/20 | 0.50 |
| ▸ | HNF4A | P41235 | 6/20 | 0.50 |
| ▸ | RARB | P10826 | 5/20 | 0.45 |
| ▸ | RARG | P13631 | 4/20 | 0.45 |
| ▸ | RARA | P10276 | 2/20 | 0.45 |
| ▸ | RXRB | P28702 | 2/20 | 0.45 |
| ▸ | RXRG | P48443 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | DRD1 | P21728 | 1/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6693435 | 0.82 | RXRA (0.62) | RXRARARBRARGRARARXRB | |
| SCHEMBL6915718 | 0.80 | RXRA (0.77) | RXRAHNF4ARARBRARGRARA | |
| SCHEMBL6679871 | 0.80 | RXRA (0.59) | RXRARARBRARGRARARXRB | |
| SCHEMBL6681154 | 0.79 | RXRA (0.65) | RXRARARBRARGRARARXRB | |
| SCHEMBL29498839 | 0.73 | RXRA (0.51) | RXRAHNF4ARARBRARGRXRB | |
| SCHEMBL22235281 | 0.73 | RXRA (0.51) | RXRAHNF4ARARBRARGRXRB | |
| SCHEMBL22235242 | 0.71 | RXRA (0.48) | RXRAHNF4ARARBRARGRARA | |
| SCHEMBL29498876 | 0.71 | RXRA (0.48) | RXRAHNF4ARARBRARGRARA | |
| SCHEMBL6915864 | 0.71 | RXRA (0.74) | RXRAHNF4ARARBRARGRARA | |
| SCHEMBL2877001 | 0.69 | TSHR (0.68) | RXRAHNF4ATSHRPLA2G4BMRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004048390-A1 | SILICON COMPOUNDS | AMEDIS PHARMACEUTICALS LTD. (GB) | 2004-06-10 | — | — | WO | claimed |
| WO-2004048390-A1 | SILICON COMPOUNDS | AMEDIS PHARMACEUTICALS LTD. (GB) | 2004-06-10 | — | — | WO | disclosed |