Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 17/20 | 0.62 |
| ▸ | RARB | P10826 | 6/20 | 0.46 |
| ▸ | RXRB | P28702 | 6/20 | 0.46 |
| ▸ | RARG | P13631 | 5/20 | 0.46 |
| ▸ | RXRG | P48443 | 5/20 | 0.46 |
| ▸ | RARA | P10276 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6681154 | 0.91 | RXRA (0.65) | RXRARARBRXRBRARGRXRG | |
| SCHEMBL6679871 | 0.84 | RXRA (0.59) | RXRARARBRXRBRARGRXRG | |
| SCHEMBL6675847 | 0.82 | RXRA (0.50) | RXRARARBRXRBRARGRXRG | |
| SCHEMBL1073916 | 0.77 | RXRA (1.00) | RXRARARBRXRBRARGRXRG | |
| SCHEMBL24066420 | 0.70 | RORA (0.61) | RXRARARBRXRBRARGRXRG | |
| SCHEMBL6676922 | 0.69 | TDP1 (0.44) | RXRARARBRXRBRARGRXRG | |
| SCHEMBL6916396 | 0.69 | RXRA (1.00) | RXRARARBRXRBRARGRXRG | |
| SCHEMBL6681171 | 0.68 | RXRA (0.61) | RXRARARBRXRBRARGRXRG | |
| SCHEMBL277909 | 0.66 | ALDH1A1 (0.54) | RXRARXRBMEN1KMT2AALDH1A1 | |
| SCHEMBL6678963 | 0.66 | RXRA (0.54) | RXRARARBRXRBRARGRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004048390-A1 | SILICON COMPOUNDS | AMEDIS PHARMACEUTICALS LTD. (GB) | 2004-06-10 | — | — | WO | claimed |
| WO-2004048390-A1 | SILICON COMPOUNDS | AMEDIS PHARMACEUTICALS LTD. (GB) | 2004-06-10 | — | — | WO | disclosed |