SCHEMBL6676409

SCHEMBL6676409

O=C(O)Oc1c[nH]c2c(C3CC3)c(Cl)c(F)cc2c1=O

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CSNK2A2 P19784 1/20 0.33
CSNK2B P67870 1/20 0.33
CSNK2A1 P68400 1/20 0.33
TNF P01375 1/20 0.31
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4962609 0.84 CSNK2A2 (0.49) CSNK2A2CSNK2BCSNK2A1ALDH1A1LMNA
SCHEMBL1421988 0.83 CSNK2A2 (0.48) CSNK2A2CSNK2BCSNK2A1ALDH1A1LMNA
SCHEMBL17769266 0.83 CSNK2A2 (0.48) CSNK2A2CSNK2BCSNK2A1ALDH1A1LMNA
SCHEMBL10875293 0.82 DNA2 (0.37) CSNK2A2CSNK2BCSNK2A1ALDH1A1LMNA
SCHEMBL5735129 0.80 KDM4E (0.39) ALDH1A1LMNA
SCHEMBL5736019 0.79 KDM4E (0.41) ALDH1A1LMNA
SCHEMBL6673792 0.78 CYP1A2 (0.34) CSNK2A2CSNK2BCSNK2A1TNFALDH1A1
SCHEMBL5507782 0.77 KDM4E (0.41) ALDH1A1LMNA
SCHEMBL8320834 0.77 ALDH1A1 (0.32) ALDH1A1LMNA
SCHEMBL8561725 0.73 CYP1A2 (0.38) TNFALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004043496-A1 FLUORQUINOLINES LABELLED WITH FLUORINE-18 AUSTRIA WIRTSCHAFTSSERVICE GESELLSCHAFT M.B.H. (AT) 2004-05-27 WO disclosed