Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.33 |
| ▸ | CSNK2B | P67870 | 3/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TNF | P01375 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CLEC4M | Q9H2X3 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | GUSB | P08236 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5194351 | 0.84 | CSNK2A2 (0.50) | CYP1A2CYP3A4CYP2C19CSNK2A2CSNK2B | |
| SCHEMBL3812191 | 0.83 | CSNK2A2 (0.49) | CYP1A2CYP3A4CYP2C19CSNK2A2CSNK2B | |
| SCHEMBL17769476 | 0.80 | CYP1A2 (0.58) | CYP1A2CYP3A4CYP2C19ALDH1A1KDM4E | |
| SCHEMBL8559738 | 0.78 | KDM4E (0.39) | CYP3A4CYP2C19ALDH1A1KDM4EHPGD | |
| SCHEMBL6676409 | 0.78 | CSNK2A2 (0.33) | CSNK2A2CSNK2BCSNK2A1ALDH1A1TNF | |
| SCHEMBL4758703 | 0.74 | KDM4E (0.38) | CYP3A4CYP2C19ALDH1A1KDM4EHPGD | |
| SCHEMBL8317732 | 0.73 | LMNA (0.34) | CYP1A2CYP3A4CYP2C19ALDH1A1KDM4E | |
| SCHEMBL8318587 | 0.72 | CYP1A2 (0.33) | CYP1A2CYP3A4CYP2C19ALDH1A1KDM4E | |
| SCHEMBL17769482 | 0.71 | CSNK2A2 (0.47) | CYP1A2CYP3A4CYP2C19CSNK2A2CSNK2B | |
| SCHEMBL10760134 | 0.71 | KDM4E (0.45) | CYP1A2CYP3A4CYP2C19CSNK2A2CSNK2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004043496-A1 | FLUORQUINOLINES LABELLED WITH FLUORINE-18 | AUSTRIA WIRTSCHAFTSSERVICE GESELLSCHAFT M.B.H. (AT) | 2004-05-27 | — | — | WO | disclosed |