Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.68 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.58 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.58 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 3/20 | 0.53 |
| ▸ | CA9 | Q16790 | 3/20 | 0.53 |
| ▸ | CA1 | P00915 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3626535 | 0.82 | CA12 (0.50) | SMN1; SMN2GAAALDH1A1KDM4ES1PR2 | |
| SCHEMBL8602183 | 0.81 | CA12 (0.59) | SMN1; SMN2LMNAMAPTNPSR1TDP1 | |
| SCHEMBL11576737 | 0.81 | CA12 (0.59) | SMN1; SMN2GAAALDH1A1KDM4ELMNA | |
| SCHEMBL218536 | 0.81 | SMN1; SMN2 (0.68) | SMN1; SMN2GAAALDH1A1KDM4EGLA | |
| SCHEMBL6257441 | 0.81 | SMN1; SMN2 (0.68) | SMN1; SMN2GAAALDH1A1LMNATDP1 | |
| SCHEMBL2835133 | 0.81 | SMN1; SMN2 (0.68) | SMN1; SMN2GAAALDH1A1KDM4ES1PR2 | |
| SCHEMBL8157313 | 0.81 | SMN1; SMN2 (0.68) | SMN1; SMN2GAAVCAM1NPC1CA12 | |
| SCHEMBL3622125 | 0.80 | SMN1; SMN2 (0.67) | SMN1; SMN2GAAALDH1A1KDM4ELMNA | |
| SCHEMBL15177296 | 0.79 | SMN1; SMN2 (0.66) | SMN1; SMN2GAAALDH1A1KDM4EGLA | |
| SCHEMBL8192690 | 0.79 | SMN1; SMN2 (0.66) | SMN1; SMN2GAAALDH1A1KDM4EGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004037159-A2 | COMPOUNDS, COMPOSITIONS AND METHODS FOR MODULATING FAT METABOLISM | OBETHERAPY BIOTECHNOLOGY (FR) | 2004-05-06 | — | — | WO | disclosed |