SCHEMBL6257441

SCHEMBL6257441

Nc1ccc(S(=O)(=O)N(CCO)CCO)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.68
CA2 P00918 4/20 0.57
CA12 O43570 3/20 0.57
CA9 Q16790 3/20 0.57
CA1 P00915 3/20 0.57
GAA P10253 2/20 0.55
NPC1 O15118 1/20 0.55
BACE1 P56817 1/20 0.54
MMP1 P03956 4/20 0.49
MMP8 P22894 4/20 0.49
MMP13 P45452 4/20 0.49
MMP7 P09237 3/20 0.49
MMP12 P39900 3/20 0.49
VCAM1 P19320 1/20 0.49
TSHR P16473 3/20 0.47
ALDH1A1 P00352 1/20 0.47
NT5E P21589 1/20 0.47
LMNA P02545 1/20 0.45
MPO P05164 1/20 0.45
CYP3A4 P08684 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10119211 0.92 SMN1; SMN2 (0.58) SMN1; SMN2CA2CA12CA9CA1
SCHEMBL15759123 0.85 TAS2R14 (0.54) SMN1; SMN2CA2CA12CA9CA1
SCHEMBL8157313 0.85 SMN1; SMN2 (0.68) SMN1; SMN2CA2CA12CA9CA1
SCHEMBL10693896 0.81 CA12 (0.54) SMN1; SMN2CA2CA12CA9CA1
SCHEMBL218536 0.81 SMN1; SMN2 (0.68) SMN1; SMN2CA2CA12CA9GAA
SCHEMBL414560 0.81 CA9 (0.62) SMN1; SMN2CA2CA12CA9CA1
SCHEMBL4076826 0.81 CA12 (0.57) SMN1; SMN2CA2CA12CA9CA1
SCHEMBL2835133 0.81 SMN1; SMN2 (0.68) SMN1; SMN2CA2CA12CA9CA1
SCHEMBL6676536 0.81 SMN1; SMN2 (0.68) SMN1; SMN2CA2CA12CA9CA1
SCHEMBL3622125 0.80 SMN1; SMN2 (0.67) SMN1; SMN2CA2CA12CA9CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019078128-A1 INK, INKJET TEXTILE PRINTING METHOD, INK CARTRIDGE, INKJET PRINTER, AQUEOUS DISPERSION, POLYUREA, POLYURETHANE, COMPOUND AND COLORED FABRIC 富士フイルム株式会社 2019-04-25 WO disclosed
EP-2601268-B1 PARTICLES FOR ELECTROPHORETIC DISPLAYS MERCK PATENT GMBH (DE) 2018-03-21 EP disclosed
US-9487611-B2 Particles for electrophoretic displays MERCK PATENT GMBH (DE) 2016-11-08 US disclosed
US-9487611-B2 Particles for electrophoretic displays MERCK PATENT GMBH (DE) 2016-11-08 US disclosed
US-9383621-B2 Electrophoretic fluids MERCK PATENT GMBH (DE) 2016-07-05 US disclosed
US-9383621-B2 Electrophoretic fluids MERCK PATENT GMBH (DE) 2016-07-05 US disclosed
US-9018151-B2 Optical brighteners and compositions comprising the same MILLIKEN & COMPANY (US) 2015-04-28 US disclosed
US-20140313567-A1 ELECTROPHORETIC FLUIDS E INK CORPORATION 2014-10-23 US disclosed
US-20140313567-A1 ELECTROPHORETIC FLUIDS E INK CORPORATION 2014-10-23 US disclosed
US-8740997-B2 Optical brighteners and compositions comprising the same MILLIKEN & COMPANY (US) 2014-06-03 US disclosed
EP-0823880-A1 DYE DIFFUSION THERMAL TRANSFER PRINTING IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1998-02-18 EP disclosed
EP-0797635-A2 NON-AQUEOUS INKS AND COATINGS CONTAINING CARBON PRODUCTS CABOT CORPORATION (US) 1997-10-01 EP disclosed
WO-1996034766-A1 DYE DIFFUSION THERMAL TRANSFER PRINTING IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1996-11-07 WO disclosed
WO-1996034916-A2 INK COMPOSITION ZENECA LIMITED (GB) 1996-11-07 WO disclosed
WO-1996018694-A2 NON-AQUEOUS INKS AND COATINGS CONTAINING CARBON PRODUCTS CABOT CORPORATION (US) 1996-06-20 WO disclosed
EP-0333337-B1 Thermal transfer sheet ZENECA LTD (GB) 1994-12-21 EP disclosed
US-5102448-A Hot melt of solid ink composition IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1992-04-07 US disclosed
US-4933426-A POLYLACTONE CONTAINING BOUND DYE, WAX REPLACEMENT IN THERMAL WAX TRANSFER IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1990-06-12 US disclosed
EP-0371627-A2 Ink-jet printing ZENECA LIMITED (GB) 1990-06-06 EP disclosed
EP-0333337-A2 Thermal transfer sheet ZENECA LIMITED (GB) 1989-09-20 EP disclosed