Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.62 |
| ▸ | TPMT | P51580 | 4/20 | 0.54 |
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.47 |
| ▸ | HCAR1 | Q9BXC0 | 2/20 | 0.46 |
| ▸ | DAO | P14920 | 1/20 | 0.46 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CA3 | P07451 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2431319 | 0.89 | TTR (0.56) | TTRTPMTTSHRSRD5A2HCAR1 | |
| SCHEMBL29738515 | 0.89 | TTR (0.56) | TTRTPMTTSHRSRD5A2HCAR1 | |
| SCHEMBL8840267 | 0.88 | TTR (0.50) | TTRTPMTTSHRSRD5A2HCAR1 | |
| SCHEMBL3908489 | 0.87 | TTR (0.59) | TTRTPMTTSHRSRD5A2HCAR1 | |
| SCHEMBL23301753 | 0.85 | TPMT (0.54) | TTRTPMTTSHRSRD5A2HCAR1 | |
| SCHEMBL16994423 | 0.85 | TTR (0.52) | TTRTPMTTSHRSRD5A2HCAR1 | |
| SCHEMBL23699493 | 0.85 | TTR (0.52) | TTRTPMTTSHRSRD5A2HCAR1 | |
| SCHEMBL23630933 | 0.85 | TTR (0.52) | TTRTPMTTSHRSRD5A2HCAR1 | |
| SCHEMBL8840329 | 0.82 | TTR (0.41) | TTRTPMTTSHRSRD5A2DAO | |
| SCHEMBL3230982 | 0.82 | TTR (0.48) | TTRTPMTTSHRSRD5A2HCAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 122 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122029155-A | Heterocyclic compound and harmful arthropod control composition containing same | 住友化学株式会社 | 2026-05-12 | — | — | CN | disclosed |
| US-12617762-B2 | Carboxy derivatives with antiinflamatory properties | SITRYX THERAPEUTICS LIMITED (GB) | 2026-05-05 | — | — | US | disclosed |
| EP-4081511-B3 | CARBOXY DERIVATIVES WITH ANTIINFLAMMATORY PROPERTIES | SITRYX THERAPEUTICS LTD (GB) | 2026-03-04 | — | — | EP | disclosed |
| US-20250313574-A1 | SIALIC ACID DERIVATIVES AND METHODS OF USING SAME | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2025-10-09 | — | — | US | disclosed |
| WO-2025079605-A1 | HETEROCYCLIC COMPOUND AND HARMFUL ARTHROPOD-CONTROLLING COMPOSITION CONTAINING SAME | 住友化学株式会社 | 2025-04-17 | — | — | WO | disclosed |
| EP-4536653-A2 | SIALIC ACID DERIVATIVES AND METHODS OF USING SAME | Eisai R&D Management Co., Ltd. (JP) | 2025-04-16 | — | — | EP | disclosed |
| US-12264147-B2 | Substituted carboxamides as inhibitors of WDR5 protein-protein binding | Propellon Therapeutics Inc. (CA) | 2025-04-01 | — | — | US | disclosed |
| CN-118978698-B | Hydrophobic thermoplastic polyimide resin and preparation method thereof | 江苏集萃功能材料研究所有限公司 | 2025-02-07 | — | — | CN | disclosed |
| CN-113710668-B | Condensed azines for EP300 or CBP modulation and indications thereof | OPNA生物公司 | 2025-01-07 | — | — | CN | disclosed |
| CN-118978698-A | Hydrophobic thermoplastic polyimide resin and preparation method thereof | 江苏集萃功能材料研究所有限公司 | 2024-11-19 | — | — | CN | disclosed |
| US-20050153963-A1 | N-[phenyl (piperidin-2-yl) methyl]benzamide derivatives, preparation thereof, and use thereof in therapy | SANOFI-AVENTIS (FR) | 2005-07-14 | — | — | US | disclosed |
| WO-2004078924-A2 | BIOAVAILABLE DIACYLHYDRAZINE LIGANDS FOR MODULATING THE EXPRESSION OF EXOGENOUS GENES VIA AN ECDYSONE RECEPTOR COMPLEX | RHEOGENE, INC. (US) | 2004-09-16 | — | — | WO | disclosed |
| US-20030216577-A1 | Preparation of aromatic and heteroaromatic carboxylic acids by catalytic ozonolysis | DSM FINE CHEMICALS AUSTRIA NFG GMBH & COKG (AT) | 2003-11-20 | — | — | US | disclosed |
| EP-1362840-A1 | Process for the preparation of aromatic and heteroaromatic carboxylic acids via catalytic ozonolysis | DSM Fine Chemicals Austria Nfg GmbH & Co KG (AT) | 2003-11-19 | — | — | EP | disclosed |
| US-5039807-A | Insecticides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-08-13 | — | — | US | disclosed |
| US-4914123-A | Acyloxythiophene derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1990-04-03 | — | — | US | disclosed |
| US-4871387-A | Pyri(mi)dyl-oxy-and -thio-benzoic acid derivatives useful as herbicides and plant growth regulants | BAYER AKTIENGESELLSCHAFT (DE) | 1989-10-03 | — | — | US | disclosed |
| US-4866078-A | Phenyl pyridones and insectidal use thereof | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-09-12 | — | — | US | disclosed |
| EP-0259048-A2 | Chemical compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-03-09 | — | — | EP | disclosed |
| EP-0226837-A2 | Pyri(mi)dyloxy and -thiobenzoic acid derivatives | BAYER AG (DE) | 1987-07-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12264147-B2 | Substituted carboxamides as inhibitors of WDR5 protein-protein binding | WDR5, WDR82, WDR1 | TTR 4426/4885TPMT 724/4885TSHR 4612/4885 |
| US-20050153963-A1 | N-[phenyl (piperidin-2-yl) methyl]benzamide derivatives, preparation thereof, and use thereof in therapy | HDAC6, NAT1, ARG2 | TTR 2272/4885TPMT 214/4885TSHR 663/4885 |
| US-20250313574-A1 | SIALIC ACID DERIVATIVES AND METHODS OF USING SAME | NEU1, NEU2, NEU4 | TTR 646/4885TPMT 2508/4885TSHR 2456/4885 |
| US-12617762-B2 | Carboxy derivatives with antiinflamatory properties | CCR1, CBR1, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | TTR 3962/4885TPMT 1005/4885TSHR 3443/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.