Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | TSHR | P16473 | 5/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | DPP4 | P27487 | 11/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4667805 | 0.90 | DPP4 (0.52) | ALDH1A1TSHRHSD17B10THRBNPSR1 | |
| SCHEMBL4668769 | 0.87 | ALDH1A1 (0.59) | ALDH1A1TSHRHSD17B10THRBNPSR1 | |
| SCHEMBL4668509 | 0.86 | DPP4 (0.57) | ALDH1A1TSHRHSD17B10THRBNPSR1 | |
| SCHEMBL4668663 | 0.82 | TSHR (0.73) | ALDH1A1TSHRHSD17B10THRBNPSR1 | |
| SCHEMBL4668748 | 0.81 | DPP4 (0.56) | ALDH1A1TSHRHSD17B10THRBNPSR1 | |
| SCHEMBL4669779 | 0.80 | DPP4 (0.58) | ALDH1A1TSHRHSD17B10THRBNPSR1 | |
| SCHEMBL6674513 | 0.80 | DPP4 (0.66) | ALDH1A1TSHRHSD17B10THRBNPSR1 | |
| SCHEMBL4668968 | 0.80 | ALDH1A1 (0.56) | ALDH1A1TSHRHSD17B10THRBNPSR1 | |
| SCHEMBL4666981 | 0.80 | TSHR (0.72) | ALDH1A1TSHRHSD17B10THRBNPSR1 | |
| SCHEMBL4668818 | 0.79 | DPP4 (0.66) | ALDH1A1TSHRHSD17B10THRBNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004033455-A2 | HEMISUCCINATE SALTS OF HETEROCYCLIC DPP-IV INHIBITORS | NOVO NORDISK A/S (DK) | 2004-04-22 | — | — | WO | disclosed |