Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | RHOC | P08134 | 1/20 | 0.42 |
| ▸ | RHOA | P61586 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6382771 | 0.83 | MTNR1A (0.65) | MTNR1AMTNR1BNPC1SMN1; SMN2POLB | |
| SCHEMBL23568434 | 0.81 | ALDH1A1 (0.48) | MTNR1AMTNR1BNPC1USP2ALOX15 | |
| SCHEMBL13293930 | 0.81 | MTNR1A (0.45) | MTNR1AMTNR1BNPC1USP2ALOX15 | |
| SCHEMBL15904295 | 0.81 | MTNR1A (0.45) | MTNR1AMTNR1BNPC1USP2ALOX15 | |
| Hydrochloric Acid SCHEMBL27202277 | 0.80 | ALDH1A1 (0.47) | MTNR1AMTNR1BNPC1USP2ALOX15 | |
| SCHEMBL6275214 | 0.77 | SMN1; SMN2 (0.47) | NPC1SMN1; SMN2ALDH1A1POLBRAB9A | |
| SCHEMBL15904166 | 0.76 | ALDH1A1 (0.52) | MTNR1AMTNR1BSMN1; SMN2ALDH1A1POLB | |
| SCHEMBL16935825 | 0.74 | POLB (0.53) | NPC1SMN1; SMN2ALDH1A1POLBRAB9A | |
| SCHEMBL23568432 | 0.74 | CA12 (0.56) | SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL613023 | 0.73 | MTNR1A (0.44) | MTNR1AMTNR1BNPC1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004045610-A1 | AMINOALCOHOL DERIVATIVES AND THEIR USE AS BETA-3 ADRENERGIC RECEPTOR AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD (JP) | 2004-06-03 | — | — | WO | disclosed |