Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4508034 | 0.95 | P2RX7 (0.72) | P2RX7P2RX3 | |
| SCHEMBL4513243 | 0.95 | P2RX7 (0.72) | P2RX7P2RX3 | |
| SCHEMBL6617703 | 0.95 | P2RX7 (0.72) | P2RX7P2RX3 | |
| SCHEMBL4507991 | 0.92 | P2RX7 (0.89) | P2RX7P2RX3 | |
| SCHEMBL4497761 | 0.88 | P2RX7 (0.73) | P2RX7P2RX3 | |
| SCHEMBL4507561 | 0.87 | P2RX7 (0.80) | P2RX7P2RX3 | |
| SCHEMBL29475619 | 0.87 | P2RX7 (1.00) | P2RX7P2RX3 | |
| SCHEMBL12891317 | 0.87 | P2RX7 (1.00) | P2RX7P2RX3 | |
| SCHEMBL4494620 | 0.87 | P2RX7 (0.73) | P2RX7P2RX3 | |
| SCHEMBL4513258 | 0.86 | P2RX7 (1.00) | P2RX7P2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1490341-A1 | NOVEL ADAMANTANE DERIVATIVES | AstraZeneca AB (SE) | 2004-12-29 | — | — | EP | disclosed |
| WO-2003080579-A1 | NOVEL ADAMANTANE DERIVATIVES | ASTRAZENECA AB (SE) | 2003-10-02 | — | — | WO | disclosed |