Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CASR | P41180 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6675653 | 0.99 | DPP4 (0.37) | HTTCASRALDH1A1DPP4LMNA | |
| SCHEMBL6680855 | 0.89 | HTT (0.45) | HTTCASRALDH1A1LMNAHTR6 | |
| Hydrochloric Acid SCHEMBL6676152 | 0.88 | HTT (0.44) | HTTCASRALDH1A1LMNAHTR6 | |
| SCHEMBL6677744 | 0.83 | HTR6 (0.38) | HTTALDH1A1LMNAPOLBHTR6 | |
| Hydrochloric Acid SCHEMBL6680953 | 0.82 | KMT2A (0.39) | HTTALDH1A1LMNAPOLBHTR6 | |
| SCHEMBL6682225 | 0.79 | TAAR1 (0.49) | HTTHTR6 | |
| SCHEMBL7244882 | 0.78 | ALDH1A1 (0.44) | HTTALDH1A1LMNA | |
| SCHEMBL6675274 | 0.77 | TDP1 (0.44) | HTTALDH1A1LMNATDP1 | |
| SCHEMBL6679151 | 0.77 | ALDH1A1 (0.42) | HTTALDH1A1LMNAPOLBHTR6 | |
| Hydrochloric Acid SCHEMBL6676248 | 0.76 | TDP1 (0.43) | HTTALDH1A1LMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798292-B1 | ANILINE DERIVATIVES HAVING NITROGEN MONOXIDE SYNTHASE INHIBITORY ACTIVITY | CHUGAI SEIYAKUKABUSHIKI KAISHA (JP) | 2004-11-03 | — | — | EP | claimed |