Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 17/20 | 0.52 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.52 |
| ▸ | LPAR5 | Q9H1C0 | 12/20 | 0.50 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6677763 | 0.92 | LPAR1 (0.47) | LPAR1LPAR3LPAR5 | |
| SCHEMBL6799367 | 0.90 | LPAR1 (0.47) | LPAR1LPAR3LPAR5 | |
| SCHEMBL6802925 | 0.87 | LPAR1 (0.46) | LPAR1LPAR3LPAR5TAS2R14 | |
| SCHEMBL6540329 | 0.85 | TAS2R14 (0.54) | LPAR1LPAR5TAS2R14 | |
| SCHEMBL6676710 | 0.84 | POLB (0.47) | LPAR1LPAR5TAS2R14 | |
| SCHEMBL6540085 | 0.83 | ALDH1A1 (0.50) | LPAR1 | |
| SCHEMBL6802977 | 0.82 | CA12 (0.46) | LPAR1 | |
| SCHEMBL6676692 | 0.82 | LPAR1 (0.59) | LPAR1LPAR5TAS2R14 | |
| SCHEMBL6274486 | 0.82 | FOLH1 (0.43) | — | |
| SCHEMBL6677130 | 0.79 | LPAR1 (0.51) | LPAR1LPAR5TAS2R14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040106653-A1 | Aminoalcohol derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-06-03 | — | — | US | disclosed |
| WO-2004045610-A1 | AMINOALCOHOL DERIVATIVES AND THEIR USE AS BETA-3 ADRENERGIC RECEPTOR AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD (JP) | 2004-06-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040106653-A1 | Aminoalcohol derivatives | FANCD2, FANCI, HRH2 | LPAR1 1110/4885LPAR3 729/4885LPAR5 1485/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.