⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7766524 | 0.84 | ALDH1A1 (0.41) | — | |
| SCHEMBL384128 | 0.84 | ALDH1A1 (0.37) | — | |
| SCHEMBL5172826 | 0.83 | ALDH1A1 (0.34) | — | |
| SCHEMBL8307132 | 0.83 | ALDH1A1 (0.34) | — | |
| Hydrochloric Acid SCHEMBL2493637 | 0.83 | ALDH1A1 (0.40) | — | |
| SCHEMBL9063985 | 0.83 | ALDH1A1 (0.40) | — | |
| SCHEMBL22404 | 0.81 | — | — | |
| SCHEMBL145933 | 0.81 | — | — | |
| SCHEMBL10642839 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL2256139 | 0.79 | NPC1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100137206-A1 | NOVEL LIGAND GUIDED BLOCK COPOLYMERS FOR TARGETED DRUG DELIVERY | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2010-06-03 | — | — | US | claimed |
| WO-2008071009-A1 | NOVEL LIGAND GUIDED BLOCK COPOLYMERS FOR TARGETED DRUG DELIVERY | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2008-06-19 | — | — | WO | claimed |
| EP-1529247-A1 | USE OF SALTS OF LAYERED DOUBLE HYDROXIDES | Clariant GmbH (DE) | 2005-05-11 | — | — | EP | claimed |
| WO-2004019138-A1 | USE OF SALTS OF LAYERED DOUBLE HYDROXIDES | CLARIANT GMBH (DE) | 2004-03-04 | — | — | WO | claimed |
| EP-1209205-A1 | Improved process and method for the preparation of asymetric monofunctionalised indocyanine labelling reagents and obtained compounds | Innosense S.r.l. (IT) | 2002-05-29 | — | — | EP | claimed |
| EP-0923566-A4 | HIGH MOLECULAR WEIGHT POLYMER-BASED PRODRUGS | ENZON INC (US) | 2001-10-10 | — | — | EP | claimed |
| JP-2000517304-A | — | — | 2000-12-26 | — | — | JP | claimed |
| US-6011042-A | POLYMERIC PRODRUGS ARE PREFERABLY ESTERS OF HYDROXYL-CONTAINING AROMATIC COMPOUNDS AND ARE FORMED BY REACTING A DESIRED AROMATIC, HYDROXYL-CONTAINING COMPOUND WITH A SUBSTANTIALLY NON-ANTIGENIC POLYMER | ENZON, INC. (US) | 2000-01-04 | — | — | US | claimed |
| US-5965566-A | A WATER SOLUBLE BIOLOGICAL ACTIVE DRUG CONJUGATED WITH POLYOXYETHYLENE GLYCOL THROUGH A HYDROLYZABLE ESTER LINKAGING SPACER; CONTROLLED RELEASE PROPERTIES | ENZON, INC. (US) | 1999-10-12 | — | — | US | claimed |
| EP-0923566-A1 | HIGH MOLECULAR WEIGHT POLYMER-BASED PRODRUGS | ENZON, INC. (US) | 1999-06-23 | — | — | EP | claimed |
| WO-1998007713-A1 | HIGH MOLECULAR WEIGHT POLYMER-BASED PRODRUGS | ENZON, INC. (US) | 1998-02-26 | — | — | WO | claimed |
| WO-2023151897-A1 | TOFA ANALOGUES, SEBUM REDUCTION PREPARATIONS CONTAINING SAID TYPE OF ANALOGUES AND THE COSMETIC AND/OR THERAPEUTIC USE OF SAID TYPE OF ANALOGUES AS AN EFFECTIVE PRINCIPLE FOR REDUCING OR PREVENTING SEBUM | BEIERSDORF AG (DE) | 2023-08-17 | — | — | WO | disclosed |
| CN-105503889-B | Oligomer-opioid agonist conjugates | 尼克塔治疗公司 | 2019-12-24 | — | — | CN | disclosed |
| EP-1638538-B1 | DOSAGE FORM | THE UNIV OF HULL (GB) | 2018-02-14 | — | — | EP | disclosed |
| US-8586681-B2 | Multi-arm block copolymers as drug delivery vehicles | NEKTAR THERAPEUTICS (US) | 2013-11-19 | — | — | US | disclosed |
| EP-0137993-A2 | 11-Piperazinyl-5H-imidazo[2,1-c][1,4]benzodiazepines, process for their preparation and intermediates and medicaments containing them | BOEHRINGER INGELHEIM KG (DE) | 1985-04-24 | — | — | EP | disclosed |
| EP-0065131-A2 | Dihalogenated imidazole-carboxylic-acid-alkoxyamides, process for their preparation and their application as herbicides | BAYER AG (DE) | 1982-11-24 | — | — | EP | disclosed |
| EP-0057872-A2 | Dihalogenated imidazole-2-carboxamides, process for their preparation and their herbicidal application | BAYER AG (DE) | 1982-08-18 | — | — | EP | disclosed |
| EP-0032199-A1 | Plant growth regulating agents, their preparation and their use | BAYER AG (DE) | 1981-07-22 | — | — | EP | disclosed |
| EP-0031086-A1 | Halogenated derivatives of imidazole-carboxylic acids, process for their preparation and their use as herbicides | BAYER AG (DE) | 1981-07-01 | — | — | EP | disclosed |