SCHEMBL7766524

SCHEMBL7766524

O=C(Oc1ncc[nH]1)C(=O)Oc1ncc[nH]1

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.41
KDM4E B2RXH2 2/20 0.41
CSNK1A1 P48729 1/20 0.37
TYRO3 Q06418 1/20 0.37
DYRK1B Q9Y463 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.36
NPC1 O15118 2/20 0.35
RAB9A P51151 2/20 0.35
NISCH Q9Y2I1 2/20 0.34
MTOR P42345 1/20 0.34
ADK P55263 1/20 0.34
TBXAS1 P24557 2/20 0.34
SMPD3 Q9NY59 1/20 0.34
KMT2A Q03164 1/20 0.33
FDPS P14324 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9063985 0.98 ALDH1A1 (0.40) ALDH1A1KDM4ECSNK1A1TYRO3DYRK1B
Hydrochloric Acid SCHEMBL2493637 0.98 ALDH1A1 (0.40) ALDH1A1KDM4ECSNK1A1TYRO3DYRK1B
SCHEMBL6663245 0.88 ALDH1A1 (0.40) ALDH1A1KDM4ECSNK1A1TYRO3DYRK1B
SCHEMBL384128 0.86 ALDH1A1 (0.37) ALDH1A1KDM4ECSNK1A1TYRO3DYRK1B
SCHEMBL17363293 0.85 ALDH1A1 (0.38) ALDH1A1KDM4ECSNK1A1TYRO3DYRK1B
SCHEMBL667770 0.84
SCHEMBL15208272 0.83 ALDH1A1 (0.37) ALDH1A1KDM4ECSNK1A1TYRO3DYRK1B
SCHEMBL145933 0.83
SCHEMBL22404 0.83
SCHEMBL10642839 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108219255-A A kind of antistatic quasi-polyethylene material and preparation method thereof 董燕琦 2018-06-29 CN disclosed
CN-102046562-B Process for preparing advanced ceramic powder using onium dicarboxylates SACHEM INC 2014-04-02 CN disclosed
CN-102573458-A Monoalkyl sulfosuccinates in pesticide formulations and applications as hydrotropes AKZO NOBEL CHEMICALS INT BV 2012-07-11 CN disclosed
CN-101353344-B Pyrazolyl-substituted heterocycles and their use as phytosanitary products BAYER CROPSCIENCE AG 2012-07-11 CN disclosed
CN-102438447-A Safening agent TAMINCO NV 2012-05-02 CN disclosed
CN-102046562-A Process for preparing advanced ceramic powder using onium dicarboxylates SACHEM INC 2011-05-04 CN disclosed
EP-1115705-A1 NOVEL COMPOUNDS AstraZeneca AB (SE) 2001-07-18 EP disclosed
WO-2000018736-A1 NOVEL COMPOUNDS ASTRAZENECA AB (SE) 2000-04-06 WO disclosed
US-5025083-A Process for preparation of polycarbonate DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1991-06-18 US disclosed
EP-0382250-A2 Process for preparation of polycarbonate DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1990-08-16 EP disclosed