Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4870856 | 0.82 | MEN1 (0.45) | MEN1KMT2ATHRBMAPTLMNA | |
| SCHEMBL4867013 | 0.77 | TSHR (0.64) | MEN1KMT2ATHRBMAPTLMNA | |
| SCHEMBL4871202 | 0.77 | HDAC1 (0.45) | MEN1KMT2ALMNANOTUMHDAC1 | |
| SCHEMBL6677980 | 0.73 | MEN1 (0.45) | MEN1KMT2ATHRBMAPTRXFP1 | |
| SCHEMBL4868662 | 0.72 | LMNA (0.45) | MEN1KMT2AMAPTLMNAPOLB | |
| SCHEMBL4871913 | 0.72 | KMT2A (0.50) | MEN1KMT2ATHRBMAPTRXFP1 | |
| SCHEMBL6677985 | 0.71 | MAPT (0.51) | MEN1KMT2ATHRBMAPTRXFP1 | |
| SCHEMBL4863306 | 0.70 | THRB (0.42) | MEN1KMT2ATHRBMAPTRXFP1 | |
| SCHEMBL4871095 | 0.70 | MAPT (0.43) | MEN1KMT2ATHRBMAPTRXFP1 | |
| SCHEMBL19859267 | 0.70 | NOTUM (0.58) | KMT2ATHRBMAPTRXFP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1475368-A1 | N-CARBAMOYL NITROGEN-CONTAINING FUSED RING COMPOUNDS AND DRUGS CONTAINING THESE COMPOUNDS AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2004-11-10 | — | — | EP | disclosed |