Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NQO2 | P16083 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7712356 | 0.79 | ALDH1A1 (0.55) | PARP1KDRALDH1A1TSHRKDM4E | |
| SCHEMBL5706967 | 0.73 | KDM4E (0.47) | KDRALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL7461243 | 0.72 | PARP1 (0.44) | PARP1ALDH1A1TSHRKDM4EMEN1 | |
| SCHEMBL29937185 | 0.72 | PARP1 (0.44) | PARP1ALDH1A1TSHRKDM4EMEN1 | |
| SCHEMBL8810067 | 0.72 | PARP1 (0.44) | PARP1ALDH1A1TSHRKDM4EMEN1 | |
| SCHEMBL18451257 | 0.72 | AR (0.32) | ALDH1A1MEN1KMT2A | |
| SCHEMBL2707598 | 0.71 | PARP1 (0.43) | PARP1ALDH1A1TSHRGRIN1GRIN2A | |
| SCHEMBL6465602 | 0.70 | PARP1 (0.50) | PARP1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL29404834 | 0.70 | PARP1 (0.50) | PARP1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL10466001 | 0.70 | POLB (0.45) | PARP1ALDH1A1TSHRKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1315702-B1 | PROCESS TO PRODUCE HALO-4-PHENOXYQUINOLINES | DOW AGROSCIENCES LLC (US) | 2004-11-10 | — | — | EP | disclosed |
| US-20040044217-A1 | Process to produce halo-4-phenoxyquinolines | KRUMEL KARL LEOPOLD (US) | 2004-03-04 | — | — | US | disclosed |
| EP-1315702-A2 | PROCESS TO PRODUCE HALO-4-PHENOXYQUINOLINES | Dow AgroSciences LLC (US) | 2003-06-04 | — | — | EP | disclosed |
| WO-2002020490-A2 | PROCESS TO PRODUCE HALO-4-PHENOXYQUINOLINES | DOW AGROSCIENCES LLC (US) | 2002-03-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040044217-A1 | Process to produce halo-4-phenoxyquinolines | KCNQ4, CYP4X1, KCNQ2 | PARP1 1146/4885KDR 3959/4885ALDH1A1 2639/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.