Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.38 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9691086 | 0.83 | KDM4E (0.42) | ALDH1A1MEN1KMT2AHSD17B10TSHR | |
| SCHEMBL7048084 | 0.81 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2AHSD17B10TSHR | |
| SCHEMBL7047957 | 0.81 | AKR1C2 (0.51) | ALDH1A1MEN1KMT2AHSD17B10TSHR | |
| SCHEMBL29617335 | 0.81 | AKR1C2 (0.51) | ALDH1A1MEN1KMT2AHSD17B10TSHR | |
| SCHEMBL6678089 | 0.79 | PARP1 (0.44) | ALDH1A1MEN1KMT2AHSD17B10TSHR | |
| SCHEMBL28455106 | 0.79 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2ATSHRKDM4E | |
| SCHEMBL9690100 | 0.77 | XDH (0.37) | ALDH1A1MEN1KMT2AHSD17B10TSHR | |
| SCHEMBL9354205 | 0.77 | ALDH1A1 (0.42) | ALDH1A1HSD17B10TSHRKDM4EHPGD | |
| SCHEMBL11669054 | 0.77 | TSHR (0.47) | ALDH1A1MEN1KMT2AHSD17B10TSHR | |
| SCHEMBL9655344 | 0.76 | ALDH1A1 (0.39) | ALDH1A1MEN1KMT2AHSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111675653-A | Preparation method and application of impurities of 4-aminoquinoline compound | 珠海润都制药股份有限公司 | 2020-09-18 | — | — | CN | claimed |
| US-6362340-B1 | HEATING 4-HYDROXYQUINOLINECARBOXYLIC ACID; CONTROLLING TEMPERATURE | Chimie, Rhodia (FR) | 2002-03-26 | — | — | US | claimed |
| CN-1329598-A | Method for preparing 4-hydroquinolines and/or tautomeric compounds | RHODIA CHIMIE SA (FR) | 2002-01-02 | — | — | CN | claimed |
| CN-111675653-A | Preparation method and application of impurities of 4-aminoquinoline compound | 珠海润都制药股份有限公司 | 2020-09-18 | — | — | CN | disclosed |
| CN-111675653-A | Preparation method and application of impurities of 4-aminoquinoline compound | 珠海润都制药股份有限公司 | 2020-09-18 | — | — | CN | disclosed |