Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.47 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | GBA1 | P04062 | 1/20 | 0.44 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6153577 | 0.81 | NOTUM (0.65) | MAPTMEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL6154672 | 0.77 | GUSB (0.61) | MAPTMEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL6154281 | 0.76 | NOTUM (0.57) | MAPTMEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL6154211 | 0.75 | NOTUM (0.54) | MAPTMEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL6677750 | 0.74 | KDM4E (0.61) | MAPTMEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL6153921 | 0.74 | NOTUM (0.53) | MAPTMEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL6154585 | 0.74 | NOTUM (0.53) | MAPTMEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL8752425 | 0.74 | MEN1 (0.97) | MAPTMEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL6156315 | 0.73 | ALDH1A1 (0.54) | MAPTMEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL6154361 | 0.73 | KDM4E (0.60) | MAPTMEN1KMT2AHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869811-B1 | IMMUNOLOGICALLY ACTIVE MISTLETOE EXTRACT PREPARATIONS | MADAUS AG (DE) | 2004-08-11 | — | — | EP | claimed |
| EP-1446110-A2 | ORGANOSULFUR INHIBITORS OF TYROSINE PHOSPHATASES | Structural Bioinformatics Inc. (US) | 2004-08-18 | — | — | EP | disclosed |
| WO-2003032916-A2 | ORGANOSULFUR INHIBITORS OF TYROSINE PHOSPHATASES | STRUCTURAL BIOINFORMATICS INC. (US) | 2003-04-24 | — | — | WO | disclosed |