⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6678620 | 1.00 | — | — | |
| SCHEMBL7938678 | 1.00 | — | — | |
| SCHEMBL2567417 | 0.83 | — | — | |
| SCHEMBL1661277 | 0.83 | — | — | |
| SCHEMBL17732217 | 0.83 | — | — | |
| SCHEMBL9148718 | 0.81 | — | — | |
| SCHEMBL9148725 | 0.81 | — | — | |
| SCHEMBL7858341 | 0.77 | CYP1A2 (0.33) | — | |
| SCHEMBL7858344 | 0.77 | CYP1A2 (0.33) | — | |
| SCHEMBL7858338 | 0.77 | CYP1A2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119039223-B | Preparation method of nitrogen-containing heteroaromatic derivative and intermediate thereof | 江苏豪森药业集团有限公司 | 2025-02-25 | — | — | CN | disclosed |
| CN-119039223-A | Preparation method of nitrogen-containing heteroaromatic derivative and intermediate thereof | 江苏豪森药业集团有限公司 | 2024-11-29 | — | — | CN | disclosed |
| CN-1200917-C | Process for preparation of cyclopropyl acethlene derivative | KURARAY CO (JP) | 2005-05-11 | — | — | CN | disclosed |
| CN-1183090-C | Method for preparation of cyclopropyl acrylic derivative | �����ɷ� | 2005-01-05 | — | — | CN | disclosed |
| EP-1261657-B1 | POLY(3-CYCLOPROPYL-3-HYDROXYPROPIONATE) AND PROCESSES FOR ITS PREPARATION AND DERIVATIVES THEREOF | EASTMAN CHEM CO (US) | 2004-11-10 | — | — | EP | disclosed |
| US-20040210030-A1 | Poly(3-cyclopropyl-3-hydroxypropionate) and processes for its preparation and derivatives thereof | HUBBS JOHN CLARK (US) | 2004-10-21 | — | — | US | disclosed |
| US-6710206-B2 | HEATING TO DEHYDROGENATE AND FORM 3-CYCLOPROPYLACRYLIC ACID; VINYLCYCLOPROPANE AND CYCLOPROPYLACETYLENE PREPARATION | EASTMAN CHEMICAL COMPANY | 2004-03-23 | — | — | US | disclosed |
| US-20030212294-A1 | Poly(3-cyclopropyl-3-hydroxypropionate) and processes for its preparation and derivatives thereof | HUBBS JOHN CLARK (US) | 2003-11-13 | — | — | US | disclosed |
| US-20030208092-A1 | Poly(3-cyclopropyl-3-hydroxypropionate) and processes for its preparation and derivatives thereof | HUBBS JOHN CLARK (US) | 2003-11-06 | — | — | US | disclosed |
| US-6610878-B1 | Catalytic reaction of cyclopropanecarboxaldehyde and ketene; intermediates to vinylcyclopropane, cyclopropylacetylene and cyclopropylacrylic; inexpensive | EASTMAN CHEMICAL COMPANY | 2003-08-26 | — | — | US | disclosed |
| CN-1281840-A | Process for preparation of cyclopropyl acethlene derivative | KURARAY CO (JP) | 2001-01-31 | — | — | CN | disclosed |
| CN-1281846-A | Method for preparation of cyclopropyl acrylic derivative | KURARAY CO (JP) | 2001-01-31 | — | — | CN | disclosed |
| WO-2000068290-A2 | POLY(3-CYCLOPROPYL-3-HYDROXYPROPIONATE) AND PROCESSES FOR ITS PREPARATION AND DERIVATIVES THEREOF | EASTMAN CHEMICAL COMPANY (US) | 2000-11-16 | — | — | WO | disclosed |
| CN-1265087-A | Process for prepn. of cyclopropylacetylene | DU PONT PHARM CO (US) | 2000-08-30 | — | — | CN | disclosed |
| EP-1000001-A1 | A PROCESS FOR THE PREPARATION OF CYCLOPROPYLACETYLENE | Dupont Pharmaceuticals Company (US) | 2000-05-17 | — | — | EP | disclosed |
| US-6049019-A | Process for the preparation of cyclopropylacetylene | DUPONT PHARMACEUTICALS (US) | 2000-04-11 | — | — | US | disclosed |
| US-5955627-A | Process for the preparation of cyclopropylacetylene derivatives | KURARAY CO., LTD. (JP) | 1999-09-21 | — | — | US | disclosed |
| WO-1999006341-A1 | A PROCESS FOR THE PREPARATION OF CYCLOPROPYLACETYLENE | DUPONT PHARMACEUTICALS COMPANY (US) | 1999-02-11 | — | — | WO | disclosed |
| CN-1191856-A | Process for preparing cyclopropyl acetylene derivatives | KURARAY CO (JP) | 1998-09-02 | — | — | CN | disclosed |
| EP-0847974-A1 | Process for the preparation of cyclopropylacetylene and its derivatives | KURARAY CO., LTD. (JP) | 1998-06-17 | — | — | EP | disclosed |