SCHEMBL1661277

SCHEMBL1661277

BrC=CC1CCCCC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2567417 1.00
SCHEMBL17732217 1.00
SCHEMBL27803901 0.97
SCHEMBL6678622 0.83
SCHEMBL6678620 0.83
SCHEMBL7938678 0.83
SCHEMBL1305017 0.79 ALDH1A1 (0.33)
SCHEMBL6049736 0.79 ALDH1A1 (0.33)
SCHEMBL8155752 0.79 ALDH1A1 (0.33)
SCHEMBL11324624 0.79 ALDH1A1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180127447-A1 METATHESIS CATALYSTS AND METHODS THEREOF NATIONAL INSTITUTES OF HEALTH 2018-05-10 US disclosed
US-9850268-B2 Metathesis catalysts and methods thereof TRUSTEES OF BOSTON COLLEGE (US) 2017-12-26 US disclosed
EP-3215516-A1 METATHESIS CATALYSTS AND METHODS THEREOF Massachusetts Institute Of Technology (US) 2017-09-13 EP disclosed
EP-2382199-B1 KETAL AMIDE COMPOUNDS, METHODS OF MAKING, AND APPLICATIONS GFBIOCHEMICALS LTD (MT) 2016-11-16 EP disclosed
US-20160194343-A1 METATHESIS CATALYSTS AND METHODS THEREOF NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2016-07-07 US disclosed
WO-2016073750-A1 METATHESIS CATALYSTS AND METHODS THEREOF MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2016-05-12 WO disclosed
US-20150175568-A1 KETAL AMIDE COMPOUNDS, METHODS OF MAKING, AND APPLICATIONS GFBIOCHEMICALS LIMITED (MT) 2015-06-25 US disclosed
US-8969559-B2 Ketal amide compounds, methods of making, and applications SEGETIS, INC. (US) 2015-03-03 US disclosed
US-20130053564-A1 KETAL AMIDE COMPOUNDS, METHODS OF MAKING, AND APPLICATIONS SEGETIS, INC. (US) 2013-02-28 US disclosed
CN-102245588-A Ketal amide compounds, methods of making, and applications SEGETIS INC 2011-11-16 CN disclosed
EP-2382199-A1 KETAL AMIDE COMPOUNDS, METHODS OF MAKING, AND APPLICATIONS Segetis, Inc. (US) 2011-11-02 EP disclosed
EP-2306994-A1 S1P1 RECEPTOR AGONISTS AND USE THEREOF Amgen, Inc (US) 2011-04-13 EP disclosed
WO-2010075330-A1 KETAL AMIDE COMPOUNDS, METHODS OF MAKING, AND APPLICATIONS SEGETIS, INC. (US) 2010-07-01 WO disclosed
WO-2009154775-A1 S1P1 RECEPTOR AGONISTS AND USE THEREOF AMGEN INC. (US) 2009-12-23 WO disclosed