⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1661277 | 1.00 | — | — | |
| SCHEMBL17732217 | 1.00 | — | — | |
| SCHEMBL27803901 | 0.97 | — | — | |
| SCHEMBL6678622 | 0.83 | — | — | |
| SCHEMBL6678620 | 0.83 | — | — | |
| SCHEMBL7938678 | 0.83 | — | — | |
| SCHEMBL1305017 | 0.79 | ALDH1A1 (0.33) | — | |
| SCHEMBL6049736 | 0.79 | ALDH1A1 (0.33) | — | |
| SCHEMBL8155752 | 0.79 | ALDH1A1 (0.33) | — | |
| SCHEMBL11324624 | 0.79 | ALDH1A1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11773078-B2 | Furin inhibitors | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2023-10-03 | — | — | US | disclosed |
| EP-2382199-B1 | KETAL AMIDE COMPOUNDS, METHODS OF MAKING, AND APPLICATIONS | GFBIOCHEMICALS LTD (MT) | 2016-11-16 | — | — | EP | disclosed |
| US-20150175568-A1 | KETAL AMIDE COMPOUNDS, METHODS OF MAKING, AND APPLICATIONS | GFBIOCHEMICALS LIMITED (MT) | 2015-06-25 | — | — | US | disclosed |
| US-8969559-B2 | Ketal amide compounds, methods of making, and applications | SEGETIS, INC. (US) | 2015-03-03 | — | — | US | disclosed |
| US-20130053564-A1 | KETAL AMIDE COMPOUNDS, METHODS OF MAKING, AND APPLICATIONS | SEGETIS, INC. (US) | 2013-02-28 | — | — | US | disclosed |
| EP-2382199-A1 | KETAL AMIDE COMPOUNDS, METHODS OF MAKING, AND APPLICATIONS | Segetis, Inc. (US) | 2011-11-02 | — | — | EP | disclosed |
| WO-2010075330-A1 | KETAL AMIDE COMPOUNDS, METHODS OF MAKING, AND APPLICATIONS | SEGETIS, INC. (US) | 2010-07-01 | — | — | WO | disclosed |