Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 19/20 | 0.53 |
| ▸ | ITGA2B | P08514 | 16/20 | 0.53 |
| ▸ | ITGAV | P06756 | 5/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6677682 | 0.90 | ITGB3 (0.54) | ITGB3ITGA2BITGAV | |
| SCHEMBL6678683 | 0.88 | ITGB3 (0.57) | ITGB3ITGA2BITGAV | |
| SCHEMBL6677727 | 0.88 | ITGB3 (0.57) | ITGB3ITGA2BITGAV | |
| SCHEMBL6677738 | 0.84 | ITGB3 (0.62) | ITGB3ITGA2BITGAV | |
| SCHEMBL6676580 | 0.80 | ITGB3 (0.48) | ITGB3ITGA2BITGAVNAMPT | |
| SCHEMBL7435601 | 0.79 | ITGB3 (0.59) | ITGB3ITGA2BITGAVNAMPT | |
| SCHEMBL7435590 | 0.79 | ITGB3 (0.59) | ITGB3ITGA2BITGAVNAMPT | |
| SCHEMBL6675234 | 0.78 | ITGB3 (0.48) | ITGB3ITGA2BITGAV | |
| SCHEMBL6677677 | 0.77 | ITGB3 (0.70) | ITGB3ITGA2BITGAV | |
| SCHEMBL6677664 | 0.77 | ITGB3 (0.70) | ITGB3ITGA2BITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995018619-A9 | BICYCLIC FIBRINOGEN ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2004-10-21 | — | — | WO | disclosed |
| US-6117866-A | Bicyclic fibrinogen antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 2000-09-12 | — | — | US | disclosed |