SCHEMBL6678696

SCHEMBL6678696

CN([C]=O)Oc1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA4 P22748 1/20 0.39
LMNA P02545 1/20 0.37
LTA4H P09960 3/20 0.36
TSHR P16473 1/20 0.36
L3MBTL1 Q9Y468 2/20 0.34
SMN1; SMN2 Q16637 3/20 0.34
HTT P42858 3/20 0.34
TSPO P30536 1/20 0.34
HPGD P15428 1/20 0.34
NPC1 O15118 2/20 0.33
RAB9A P51151 2/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
SLC6A2 P23975 1/20 0.33
SLC6A4 P31645 1/20 0.33
ALDH1A1 P00352 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
KDM4E B2RXH2 1/20 0.33
MAPT P10636 1/20 0.33
THRB P10828 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11078957 0.72 L3MBTL1 (0.43) CA4LMNALTA4HTSHRL3MBTL1
SCHEMBL10358829 0.72 CA4 (0.48) CA4LMNALTA4HTSHRL3MBTL1
SCHEMBL621536 0.71 L3MBTL1 (0.39) CA4LTA4HTSHRL3MBTL1HTT
Trimethylammonium SCHEMBL27736610 0.70 CA4 (0.40) CA4LMNALTA4HTSHRL3MBTL1
SCHEMBL10043046 0.69 HSP90AA1 (0.44) CA4LMNALTA4HTSHRSMN1; SMN2
SCHEMBL5645211 0.68 TSHR (0.43) TSHRL3MBTL1HPGDKMT2ASLC6A2
SCHEMBL3066976 0.68 SMN1; SMN2 (0.44) L3MBTL1SMN1; SMN2HTTTSPONPC1
SCHEMBL10657839 0.68 CA4 (0.39) CA4LMNALTA4HTSHRL3MBTL1
SCHEMBL7867520 0.67 CA4 (0.42) CA4LMNALTA4HTSHRL3MBTL1
SCHEMBL6777693 0.67 LTA4H (0.39) CA4LMNALTA4HTSHRL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004041799-A1 5- (SUBSTITUTED PHENYL) -THIADIAZOLIDINE-3-ONES AND THEIR USE AS PTP1B ASTRAZENECA AB (SE) 2004-05-21 WO disclosed
US-6613814-B2 Water-dispersed particles of an oil-soluble pyrrolotriazol-azomethine dyes and an oil-soluble polymer; reproduction, especially cyan color; waterproofing; colorfastness; storage stability; antifouling agents; paper FUJI PHOTO FILM CO., LTD. (JP) 2003-09-02 US disclosed
US-20010020055-A1 Coloring composition, ink for ink jet, and ink jet recording method FUJIFILM CORPORATION (JP) 2001-09-06 US disclosed
EP-0903350-A1 Pyrrolotriazole derivative FUJI PHOTO FILM CO., LTD. (JP) 1999-03-24 EP disclosed
EP-0423796-B1 Thermal transfer dye donating materials FUJI PHOTO FILM CO LTD (JP) 1996-05-29 EP disclosed
US-5508421-A Pyrrolotriazole azomethine dye, and heat transfer dye providing material containing a pyrrolotriazole azomethine dye FUJI PHOTO FILM CO., LTD. (JP) 1996-04-16 US disclosed
US-5403811-A Colorfast images FUJI PHOTO FILM CO., LTD. (JP) 1995-04-04 US disclosed
US-5362882-A Intermediates for dyes for polyesters, images for heat sensitive elements and electrography FUJI PHOTO FILM CO., LTD. (JP) 1994-11-08 US disclosed
US-5344933-A Pyrrole ring-or condensed pyrrole ring-containing azomethine dye FUJI PHOTO FILM CO., LTD. (JP) 1994-09-06 US disclosed
US-5262377-A Colorfastness FUJI PHOTO FILM CO., LTD. (JP) 1993-11-16 US disclosed
US-5238903-A Azo-methine dye on support FUJI PHOTO FILM CO., LTD. (JP) 1993-08-24 US disclosed
US-5227359-A Pyrazoloazole dyes FUJI PHOTO FILM CO., LTD. (JP) 1993-07-13 US disclosed
US-5210200-A Fast to heat and light FUJI PHOTO FILM CO., LTD. (JP) 1993-05-11 US disclosed
EP-0518238-A1 Pyrrolotriazole derivative FUJI PHOTO FILM CO., LTD. (JP) 1992-12-16 EP disclosed
US-5122611-A Oxidative condensation of active methylene or methine containing compound with a p-phenylene diamine component in methylene chloride solvent FUJI PHOTO FILM CO., LTD. (JP) 1992-06-16 US disclosed
US-5034371-A Cyan, yellow and magenta dyes FUJI PHOTO FILM CO., LTD. (JP) 1991-07-23 US disclosed
EP-0423796-A1 Thermal transfer dye donating materials FUJI PHOTO FILM CO., LTD. (JP) 1991-04-24 EP disclosed
US-4975409-A Ketone imine dyes; colorfastness; copies FUJI PHOTO FILM CO., LTD. (JP) 1990-12-04 US disclosed